Sentences with word «immunosurveillance»

«Recent successes in cancer immunotherapy — in the form of immune checkpoint inhibitors and adoptive T cell transfer — demonstrate how activated immune cells can eradicate tumors, but until now we didn't fully appreciate immunosurveillance or the role of adaptive immunity in tumor formation,» said senior author Michael Karin, PhD, Distinguished Professor of Pharmacology and Pathology at UC San Diego School of Medicine.

But University of California San Diego School of Medicine researchers have now found that chronic liver inflammation also promotes cancer by suppressing immunosurveillance — a natural defense mechanism in which it's thought the immune system suppresses cancer development.

The Dellabona / Casorati lab investigates T cell responses in tumor immunosurveillance and immunotherapy, by combining a variety of approaches in pre-clinical and clinical models.

The results of her project will help scientists develop novel therapies to target the regulatory proteins that cause CD47 overproduction in leukemia and other cancer stem cells, with the goal of restoring immunosurveillance and enabling the immune system to recognize and destroy these aberrant cancer cells.

Type - I interferons (IFNs) play a key role in the immune defences against viral and bacterial infections, and in cancer immunosurveillance.

Cancer immunology studies the relationship between cancer and the body's immune system, including its innate ability to prevent or eliminate cancer cells, called immunosurveillance.

This study adds to the discussion about the role of this immunosurveillance in the risk of developing the common cancers among those with compromised immune systems,» adds first author Paul Mayor, MD, Fellow in the Department of Gynecologic Oncology at RPCI.

This theory is one of infection risk: as you exercise, immunosurveillance (positive immunity) goes up and chance of infection goes down.