Sentences with phrase «in brain slices»

These findings were confirmed by two - photon imaging of neurons in the brains of living mice by the lab of collaborator Yi Zuo, PhD, a neuroscientist at UC Santa Cruz, as well as electrophysiological recordings from neurons in brain slices by the lab of collaborator Vikaas Sohal, MD, PhD, an associate professor of psychiatry at UCSF.

Via the pipette a red dye diffuses into the cell, rendering them visible in the brain slice.

No other researcher had found evidence that neurons can breach the wall between these regions, but developmental neurobiologist Pasko Rakic thought he saw hints of such a migration in brain slices he examined in 1969.

When the scientists tried to trigger LTP in these brain slices with electrical stimulation or chemicals, they found that methods that fired up cellular pathways involving the molecule cyclic adenosine monophosphate (cAMP) didn't work.

It also proved possible to compare the potency of desoxypipradrol with the psychostimulant drug cocaine in the brain slice preparation.

Bowling, H., Bhattacharya, A., Zhang, G., Lebowitz, J.Z., Alam, D., Smith, P.T., Kirschenbaum, K., Neubert, T.A., Vogel, C., Chao, M.V. *, and Klann, E. * (2016) BONLAC: a combinatorial proteomic technique to measure stimulus - induced translational profiles in brain slices.

In general, it has been difficult to preserve electrophysiologically viable motoneurons in brain slices from adult mammals.

We also have developed methods to visual cell type - specific de novo translation ex vivo in brain slices and in vivo in mice.

In addition, the relative roles of presynaptic and postsynaptic NMDA - Rs has been extensively analyzed in brain slices (Corlew et al., 2008; Rodriguez - Moreno and Paulsen, 2008), which PLE / CM - MK 801 may facilitate because it offers a new method for selectively blocking NMDA - Rs in defined subpopulations of neurons.

Studies of individual neurons in dishes of cultured neurons and in brain slices by co-first author Robert E. Stanley, a graduate student in the lab, revealed that neurons in the mutant mice had decreased numbers of dendritic spines, an important part of the synapses that neurons use to communicate with one another.

In brain slices from normal rats, only about 7 % of cells were the bursting type, but in rats bred to display depressionlike behavior, the number was 23 %.

In a brain slice, Olivia Masseck measures the activity of nerve cells in which she switches on their receptors using light stimulation.