Otherwise «you can't grow them very large and you will be hampered in trying to get the organoid to develop
more mature cell types and structures.»
Others have suggested that the apparent transdifferentiation might result from immature cells fusing
with mature cell types from other tissues.
Understanding both aspects of a stem cell's identity could be crucial to generate functional and
mature cell types for regenerative medicine.»
To build an in vitro model of the human glomerulus to probe deeper into its function and vulnerabilities to disease and drug toxicities, researchers have been attempting to engineer human stem cells — that in theory can give rise to
any mature cell type — so that they form into functional podocytes.