Sentences with word «meningeal»

We also infected mice with attenuated Type I parasites and detected parasites in the brain and meningeal homogenate in a number of mice between 5 and 20 days post infection (Figure 3D).

Two cats also had similar vascular changes in meningeal vessels.

Kipnis and his colleagues had previously shown that a type of white blood cell called a T cell (shown above) in the meninges is associated with significant influence on cognition and hence were curious about the role of meningeal immunity on brain function.

It was the temple area which hit the kerb, directly over the middle meningeal artery and if that pops, it's probably curtains.»

Because the brain is like every other tissue connected to the peripheral immune system through meningeal lymphatic vessels,» said Jonathan Kipnis, PhD, professor in the UVA Department of Neuroscience and director of UVA's Center for Brain Immunology and Glia (BIG).

[C and F] Total brain and meningeal T cells (CD4 plus CD8), indicators of brain region inflammation, are reported for Type III - and attenuated Type I - infected animals.

B - 1a cells in meningeal space secrete natural antibodies, which promote the proliferation of oligodendrocyte precorsors.

Brain leukocytes from uninfected controls and Type I - infected animals show a lower proportion of T cells, B cells, and neutrophils and likely correspond to meningeal leukocytes.

The brain and meningeal material was resuspended in room temperature 60 % (vol / vol) Percoll (GE Healthcare) / RPMI and overlaid with 30 % (vol / vol) Percoll / PBS and centrifuged with no acceleration or brakes for 20 minutes at 1000 g. Mononuclear cells were harvested from the gradient interface and washed twice in PBS before preparation for flow cytometric analysis.

They may especially need that if the shock and potential meningeal inflammation of vaccines is in their future.....

Bony compression, progresive meningeal hypertrophy and dural fibrosis cause; several different neurological dysfunction like cerebellovestibuler disfunction, cervical myelopathy, seizure activity, syringomyelia, ventricle dilatation and hydrocephalus

If meningeal involvement is present the CSF often contains increased protein (> 25 mg / dl) and inflammatory cells (> 5 cells / µl).16 Neutrophils and / or lymphocytes predominate the pleocytosis along with lesser numbers of macrophages and plasma cells.16, 16a

A subdural hematoma is a brain injury which involves blood collecting between the brain and the outermost meningeal part of the brain (called the dura).

Whole genome DNA was isolated from brain and meningeal homogenate using DNeasy Blood and Tissue Kit (Qiagen).

Meningeal lymphatics mediate immune cells / antigen circulation and impact neuroinflammation Antoine Louveau, University of Virginia

Day 8 through day 20 post infection with attenuated Type I parasites from two separate experiments resulted in brain and meningeal T cell numbers all significantly above uninfected animals.

The meningeal signs are monitored during the course of bed rest.

For years, researchers were convinced that the problem was either within the meningeal blood vessels, or, more often, the patients themselves.

These neurons, located in the walls of the meningeal blood vessels, began to fire and released neuropeptides, telling the brain to register pain and the blood vessels to dilate.

Prof Kipnis describes his lab's discovery that meningeal vessels directly link the brain with the lymphatic system, overturning decades of teaching that the brain lacks a direct connection to the immune system.

[B and E] Brain leukocytes were percoll purified from the remaining brain and meningeal homogenate, stained for leukocyte surface markers CD4, CD8, CD19, CD11b, and Ly6G, and assayed using flow cytometry.

[B] Brain leukocytes were percoll purified from the remaining brain and meningeal homogenate, stained for surface markers CD4, CD8, CD19, CD11b, and Ly6G, and assayed using flow cytometry.

They are usually a result of a skull fracture, as bone fragments may tear the meningeal artery that runs just beneath the skull.

If the patient suffers a meningeal tear, has bone fragments protruding from the break or has suffered contamination of the wound, the brain tissue may become infected at put the patient at risk of mental impairment.