Sentences with word «meningioma»

The panel also called for «aggressive research» on using RU486 and other drugs in the antiprogrestin class as contraceptives and as treat - ment for endometriosis, uter - ine fibroids, advanced breast cancer and meningioma brain tumours.

We are no longer recruiting dogs for a clinical trial, but we are offering to treat dogs diagnosed with meningioma with surgery and vaccine - based immunotherapy.

Raleigh's team found that a gene named FOXM1 was at the heart of aggressive meningioma growth, and a signpost of subsequently poor clinical outcomes, including death.

«Although we have identified radiation as a risk factor for meningiomas, radiation remains an important part of the treatment regimen for certain lesions, and is helping us obtain good results for our patients.»

However, approximately twenty percent of meningiomas are aggressive and can recur even after surgery and radiation therapy.

Other series reach varying conclusions; Germano et al., reported 23 cases of intracranial meningiomas in children under age 20 years and noted that 2 / 3rds were supratentorial in location, and 13 % were intraventricular [18].

In contrast, canine meningiomas tend to be more locally infiltrative and invariably lack demarcation from the normal brain tissue.

Though blocking FOXM1 could halt aggressive meningioma growth, the gene's role in regulating a host of other genes suggests that there would likely be significant «off - target» side effects.

Studies indicate that dogs undergoing surgical excision for cerebral meningiomas show an excellent prognosis for long - term survival.

Perhaps the most frequently diagnosed of these is a neoplastic disease called meningioma, which is a type of tumor that develops in the thin protective tissue — the meninges — that covers a cat's brain.

The reported outcomes have been favorable for most patients with pituitary macroadenomas and meningioma patients showing minimal neurologic symptoms at presentation.

The cerebral convexity is the most frequent location for adults with intracranial meningiomas.

The researchers also identified new links between aggressive meningioma proliferation and activation of an intercellular signaling pathway called Wnt — which typically plays a role during embryonic development and tissue formation.

His clinical practice includes the entire spectrum of brain tumors including low - grade gliomas, malignant gliomas, metastatic brain tumors, and benign tumors such as meningiomas, and acoustic neuromas.

There is disagreement among neurologists and radiation oncologists as to whether canine meningiomas should be treated with surgery plus radiation therapy, or with radiation therapy lone.

More than 50 % of cats treated with surgery for cerebral meningioma survive past 24 months.

I am 31 years old with two little ones... and 2 and a half years ago we found a very large meningioma in the center of my brain.

The authors concluded: «Overall, no increase in risk of glioma or meningioma [the two most common types of brain tumors] was observed with use of mobile phones.

Researchers analyzed records of 35 patients who were diagnosed with meningiomas before age 30.

Meningiomas comprise about one - third of all primary brain tumors, but are rare in children and young adults.

A retrospective review of all cases of pathologically confirmed meningioma within the intracranial compartment in individuals under the age of 30 years at initial diagnosis treated at our institution over the past 30 years was performed.

List of abbreviations CNS: Central nervous system WHO: World Health Organization NF2: Neurofibromatosis 2 MA: Meningioangiomatosis ECOG: Eastern cooperative oncology group ALL: Acute lymphocytic leukemia CSF: Cerebrospinal fluid RIM: Radiation - induced meningiomas FISH: Fluoroscence in - situ hybridization CT: Computed tomography MRI: Magnetic resonance imaging

By contrast, some authors report intraventricular and infratentorial meningiomas are more common in children [5,7,9].

«Often, we run out of time, but with our new molecular insights into meningioma biology we may be able to find new cures for these tumors with fewer side effects and better outcomes.»

Given that the protein produced by FOXM1 is known to transmit signals along the Wnt pathway, the new data suggests that FOXM1 and the Wnt pathway working in concert may drive subsequent meningioma proliferation.

Three patients had suspected pituitary tumors, 1 patient had suspected astrocytoma and the remaining were suspected meningiomas.

Meningiomas occur more commonly in dolichocephalic breeds such as Collies and German Shepherd dogs.

Glial cell tumors and pituitary tumors are most common in brachycephalic (dogs with short, broad heads) breeds, while meningiomas are most frequently seen in dolicocephalic (dogs with long narrow skull) breeds.

In another study, dogs treated with surgery for intrcranial meningiomas showed a median survival of 198 days with a 1 year survival rate of 30 %.

In one study dogs treated with surgery for olfactory meningiomas, showed a median survival of 138 days.

As it turned out, he had a slow - growing meningioma (brain tumor).

A more recent study of 97 dogs indicated that Golden Retrievers also have a high incidence of brain tumors, especially meningiomas.

In cats, meningiomas tend to be slower growing than their canine counterparts and are almost always well defined and have a clear demarcation between the rumor and normal brain tissue.

Examples include meningioma, astrocytoma, oligodendroglioma, ependymoma and choroid plexus tumors.

The new study found significant hypermethylation in the most aggressive meningiomas, and showed that these DNA modifications specifically silenced genes that usually inhibit FOXM1 expression and Wnt signaling.

Researchers so far have identified 14 meningioma patients who were exposed to radiation earlier in their lives.

Together, these findings suggest that hypermethylation may be an early trigger that leads to the development of aggressive forms of meningioma.

The MRI shows a large meningioma, the most common brain tumor seen in cats.

Recently, drugs such as 5 - hydroxyurea have been used to treat meningiomas, but as yet there are no data on the efficacy of this approach.

In general, dogs with meningiomas have a median survival time of 1 - 2 years.

«We now need to find out what other genes FOXM1 is activating to drive meningioma growth, and block those targets with clinical therapies,» Raleigh said.

They are doing a follow - up study on patients of all ages who have been treated at Loyola for meningiomas.

An international team of researchers has identified eight additional types of cancer linked to excess weight and obesity: stomach, liver, gall bladder, pancreas, ovary, meningioma (a type of brain tumor), thyroid cancer and the blood cancer multiple myeloma.

The study looked for two of the most common types of brain tumors — gliomas, which are often malignant, and meningiomas, which are more often benign — in people ages 20 to 79 in Denmark, Finland, Norway and Sweden between 1974 and 2003.

Obesity is associated with increased risk of developing and dying from the following cancers: breast (in postmenopausal women), ovarian, liver, gallbladder, kidney (renal cell), colon, pancreatic, gastric, esophageal (adenocarcinoma), endometrial, thyroid, multiple myeloma, and meningioma.

In people under age 30, radiation is a risk factor for a type of brain tumor called a meningioma, a Loyola University Medical Center study has found.

They include two patients who received radiation for leukemia at ages 5 and 6; one who received radiation at age 3 for a brain tumor known as a medulloblastoma; and one who received radiation for an earlier skull base tumor that appeared to be a meningioma.