Sentences with word «mesolimbic»

According to the dynamic developmental behavioral theory proposed by Sagvolden et al, a hypofunctioning mesolimbic dopamine system is largely responsible for producing alterations in behavioral reinforcement and extinction, which, in turn, disrupts learning processes.

Although antagonism of mesolimbic dopamine D (2) receptors by neuroleptics such as haloperidol attenuates positive symptoms of schizophrenia, a significant population of «resistant» patients fails to

The moderating effects of three single nucleotide polymorphisms (SNPs)(rs1042778, rs2268493 and rs237887) of the OXTR gene on mesolimbic responses to rewards were evaluated using a monetary incentive delay fMRI task.

Moll, J. et al (2006) Human Fronto - Mesolimbic Networks Guide Decisions About Charitable Donations.

Paper reference: Stacey, D. et al. «RASGRF - 2 regulates alcohol - induced reinforcement by influencing mesolimbic dopamine neurone activity and dopamine release» Proceedings of the National Academy of Sciences (PNAS) 2012 doi: 10.1073 / pnas.1211844110

We conclude that the glycemic state modulates the complex interplay between the PFC and hypothalamic and mesolimbic neural control of food - seeking behavior.

Initial analyses examined task effects in the entire group to verify the activation of the hypothesized mesolimbic reward circuitry by the task.

Thinking about things you enjoy can be almost as effective as actually doing the activity which makes you happy: «the part of the brain responsible for feeling pleasure, the mesolimbic dopamine system, can be activated when merely thinking about something pleasurable, such as drinking one's favorite brand of beer or driving one's favorite type of sports car.

And so the energy - balancing hypothalamus and the mesolimbic dopamine system have become very well connected.

Conversely, ghrelin increases an animal's sensitivity to food cues by increasing dopamine responses in the mesolimbic system, Mitchell Roitman, a behavioral neuroscientist at the University of Illinois in Chicago, and his colleagues reported in March in the Journal of Neurochemistry.

All of these chemicals (and many more) converge on the same region of the brain, the mesolimbic dopamine system.

It's true that cutting out the mesolimbic dopamine system entirely reduces an animal's motivation for food.

The reward - related, or «hedonic,» component is centralized in the mesolimbic dopamine system, areas of the brain usually referenced when we talk about the effects of sex, drugs and rock»n' roll.

This feeling of being excluded from the majority could also render physiological consequences leading to sensitisation of the mesolimbic dopamine system, heightening the risk of psychotic - like symptoms in vulnerable individuals.

Importantly, he has shown that selective inhibition of 2 - AG biosynthesis restores the GABAergic restraint of dopamine cell excitability, diminishes nicotine - induced activation of the mesolimbic dopamine projection, and reduces nicotine self - administration.

The mesolimbic dopamine system and the extended amygdala play important roles in both the rewarding and aversive effects of drugs of abuse.

Traditionally, research into the neurobiological substrate of drug addiction has focused on the mesolimbic dopamine reward circuitry.

Given the potential involvement of mesolimbic and mesocortical circuitry, activity in the substantia nigra was also assessed on an exploratory level.

«The limbic system — specifically the mesolimbic dopamine system — learns what feels good.

Most of us prefer sweets over sour and bitter foods because, evolutionarily, our mesolimbic pathway reinforces that sweet things provide a healthy source of carbohydrates for our bodies.

Evolution has resulted in the mesolimbic pathway, a brain system that deciphers these natural rewards for us.

The mesolimbic system and eating addiction: what sugar does and does not do.

As well, dopamine gets down - regulated in the hypothalamus and mesolimbic systems, making you crave simple carbs.

Let's get a wee bit technical for a moment: for our purposes, we need to think about the mesolimbic or «reward» pathway in the brain, which begins in the midbrain (one of the oldest parts of the brain!)

Mesolimbic and mesocortical dopaminergic neurons are necessary for normal exploratory behavior in rats

Studies show that when people think about helping others, they activate a part of the brain called the mesolimbic pathway, which is responsible for feelings of gratification.