Sentences with phrase «molecular machinery»

While nature has had billions of years to perfect its complex molecular machinery, modern science is only beginning to scratch the surface of what might be possible in tomorrow's world.

It's not as easy as it sounds: Under a microscope, they would probably look like utterly normal microbes, even though inside they would be hiding radically different molecular machinery.

But molecular machinery doesn't always behave the same in the test tube as it does in an intact cell, so no one knew how relevant these findings were to living creatures.

The study noted here provides numbers for the mutation rates in muscle stem cells, the stochastic damage that occurs over time as small numbers of errors slip past the highly efficient molecular machinery of cellular replication and DNA repair.

Thus, the absence of a proposed kind of molecular machinery in organisms in no way suggests its infeasibility.

LA JOLLA — Researchers at the Salk Institute have healed injured hearts of living mice by reactivating long dormant molecular machinery found in the animals» cells, a finding that could help pave...

October 21, 1994 Immortalizing agent of tumor cells found in yeast Researchers at the University of Chicago Medical Center have isolated the gene for a component of the elusive molecular machinery that plays a key role in making cancer cells immortal.

Scientists may be closer to answering a long - standing question in biology — how do the components of cells» molecular machinery work together to transmit vital gene regulatory information from one cell generation to the next?

Two different types of specialized taste cells contain the chemical receptors and intracellular molecular machinery needed to initiate the perception of taste.

Researchers are finding ways to assemble nanodevices and materials with the help of molecular machinery such as DNA and proteins as well as viruses, bacteria and other micro-organisms.

Mapping that dense molecular machinery is one of the most promising and challenging frontiers in medicine and biology.

Breaks in DNA strands associated with V (D) J cutting are normally repaired with high fidelity by finely tuned molecular machinery.

Researchers don't know how these pieces of molecular machinery prevent living things from withering, but previous work in plants suggests that the genes produce ultrastable proteins that help form the protective sugar mesh.

«In essence, OX40 activates the IL - 9 gene in T helper cells, leading to the overproduction of IL - 9 through a powerful molecular machinery of super-enhancers that regulate gene expression,» says Dr. Xian C. Li, the director of the Immunobiology & Transplant Science Center at Houston Methodist Research Institute.

We are developing a broad range of advanced fluorescence - based imaging technologies to assay the functions of the involved molecular machinery non-invasively, automate imaging to address all its molecular components, and computationally process image data to extract biochemical and biophysical parameters.

But now, a team of researchers has found a way to map an enzyme's underlying molecular machinery, revealing patterns that could allow them to predict how an enzyme behaves — and what happens when this process disrupted.

To deny the feasibility of advanced molecular machinery, one must apparently maintain either (i) that design of proteins will remain infeasible indefinitely, or (ii) that complex machines can not be made of proteins, or (iii) that protein machines can not build second - generation machines.

Because viruses have evolved such effective methods for finding their target and utilizing the host cells» own molecular machinery, scientists are modifying viruses into long - lasting therapeutic vehicles that can deliver drugs to specific cells or tissues or selectively target and destroy tumors.

Therefore, we speculated that molecular machinery found to promote EMT might also be upregulated in the cycling hypoxia - selected subpopulation.

Researchers at the University of Chicago Medical Center have isolated the gene for a component of the elusive molecular machinery that plays a key role in making cancer cells immortal, offering scientists a tantalizing target for new anticancer drugs of greater effectiveness and lower toxicity.

«By using this powerful approach, we can begin to answer many questions about the physiology and molecular machinery of human nerve cells — not just around healthy aging but pathological aging as well,» says Martin Hetzer, a Salk professor also involved in the work.

Are we nothing but made up of molecular machinery?

«This is a big step in determining the identity of key components of the molecular machinery that converts sound waves into electrical signals in the inner ear,» said the study's co-senior author, Gregory Frolenkov, of the Department of Physiology at the University of Kentucky.

Her work probes the molecular machinery that governs memories.

By dosing dogs with the gene for a myostatin precursor, Sweeney has found he can throw a wrench into the molecular machinery of myostatin signaling, removing a critical check on muscle growth and allowing deteriorating muscles to regain their strength.

Columbia Engineering researchers have, for the first time, harnessed the molecular machinery of living systems to power an integrated circuit from adenosine triphosphate (ATP), the energy currency of life.

We don't yet fully understand what the potential of molecular machinery is, but there are many applications that can be developed once we develop a deep understanding of how motion takes place in solids.»

This bundling of DNA acts as a switchboard for controlling genes» activity and directs a cell's complex molecular machinery.

Many of the same molecules have been implicated in both declarative and nondeclarative memory and in species as varied as sea slugs, fruit flies, and rodents, suggesting that the molecular machinery for memory has been widely conserved.

Scientists longing to sneak a peek at the molecular machinery of living cells came one step closer to that goal in March with the creation of lenses that break the limits of current light microscopy.

«In nature, polymerase, the molecular machinery that copies DNA within living cells, can sequence hundreds of millions of base pairs of DNA.

However, biochemical maps have long been filled with blank spaces because the available technology has had difficulty generating images of much of life's molecular machinery.

But in an Opinion paper published June 16 in Trends in Cell Biology, researchers propose that new genomic evidence derived from a deep - sea vent on the ocean floor suggests that the molecular machinery essential to eukaryotic life was probably borrowed, little by little over time, from those simpler ancestors.

«We found that the molecular machinery of autophagy guides the degradation of components of the nuclear lamina in mammals,» said senior author Shelley Berger, PhD, the Daniel S. Och University Professor in the departments of Cell & Developmental Biology, Genetics, and Biology.

New research at Rice University suggests actin filaments that control the shape of neuron cells may also be the key to the molecular machinery that forms and stores long - term memories.

They also discovered that dystrophin is a key member of the molecular machinery that enables muscle stem cells sense their orientation in the surrounding tissue.

«At a biochemical level, there is a lot of commonality between the molecular machinery in Drosophila and that in mice and humans,» said Dr. Ferguson.

Here's why: When the DNA of a bacterial gene is being transcribed into RNA, and the molecular machinery of transcription gets stuck at a bulky adduct, Mfd appears on the scene, recruits other repair proteins that snip away the damaged section of DNA, and «un-sticks» the transcription machinery so that it can resume its work.

Bob Bloomer asked how organisms» molecular machinery can run smoothly when there are so many «jumping genes» around.

A new study offers atomic - level details of the molecular machinery that allows swimming bacteria to sense their environment and change direction when needed.

By detecting the molecular machinery used by the plankton to create one of the enzymes needed to split nitrogen molecules apart, scientists appear to have discovered a new microbial source of the ocean's nitrogen - bearing nutrients.

Like all viruses, rhinovirus C uses the molecular machinery of host cells to replicate and become infectious.

These include molecular wheels, rotors, cars, and elevators, developed by the Nobel trio, that have considerable potential as components of molecular machinery.

These signals tell the complex molecular machinery that translates genes» instructions into newly produced proteins which genes to read and which ones to skip.

The scientists found that the system is involved in all the major processes of a cell — which genes are turned on and off, for example, as well as how the cell maintains its molecular machinery and converts energy into fuel.

We wanted to find the molecular machinery that allows one component of the cell to talk to another.