Sentences with word «muscarinic»

Scopolamine is a well known competitive muscarinic receptor antagonist that causes reproducible, transient impairments across multiple cognitive domains in healthy animals and non-diseased humans by decreasing central cholinergic neuronal activity [124, 125].

In particular, they noted that the outgrowth of neurites — projections from a neuronal cell body that connect it to other neurons — was constrained by activation of muscarinic acetylcholine receptors.

The acronym SLUD stands for salivation, lacrimation, urination, and defecation, which are the clinical signs associated with muscarinic cholinergic overstimulation caused by certain toxins.

In Kobilka's lab, Kruse worked on a GPCR group called muscarinic acetylcholine receptors.

First fatty acylated dipeptides to affect muscarinic receptor ligand binding.

He also worked on the related M2 muscarinic receptor, showing how multiple compounds could bind simultaneously to the same receptor.

Effects of myo - inositol versus fluoxetine and imipramine pretreatments on serotonin 5HT2A and muscarinic acetylcholine receptors in human neuroblastoma cells.

Antibodies to β adrenergic and muscarinic cholinergic receptors in patients with Chronic Fatigue Syndrome.

Muscarinic receptor M4 positive allosteric modulators attenuate central effects of cocaine...

Similar SH3 binding motifs exist in the formins, proteins that function in pattern formation in embryonic limbs of the mouse, and one subtype of the muscarinic acetylcholine receptor.

The rationale behind the project is that acetylcholine plays are role in cognitive functioning and that there is a subgroup of schizophrenia patients that have reduced density and M1 receptor binding in the hippocampus and dorsolateral prefrontal cortex that are referred to as «muscarinic receptor - deficit schizophrenia» or MRDS.

Therefore, the effect of J147 on the cholinergic system was investigated using the muscarinic receptor antagonist, scopolamine, which decreases central cholinergic neuronal activity.

Effects of muscarinic receptor antagonists on cocaine discrimination in wild - type mice and in muscarinic receptor M1, M2, and M4 receptor knockout mice Joseph L, Thomsen M. Behavioural Brain Research.

In studies to understand the molecular basis for therapeutic drug action, he showed how tiotropium bromide (Spiriva), an inhaled drug for chronic obstructive pulmonary disease and for uncontrolled asthma, recognizes and blocks the muscarinic 3 (M3) receptor.

The possibility grows out of the properties of certain receptors for the neurotransmitter acetylcholine, called «muscarinic acetylcholine receptors.»