Sentences with phrase «new therapeutic strategies»

The study of these new mouse models means an advance in the knowledge of disease's development mechanisms and an opportunity to implement new therapeutic strategies for patients.

Understanding these mechanisms underlying adult tissue regeneration may be instrumental for the development of new therapeutic strategies, both in regenerative and developmental medicine.

So scientists have begun looking for other targets for which they can develop new therapeutic strategies.

In fact, at the end of my studies, I spent two years doing clinical research into the development of new therapeutic strategies — a project that perfectly combined clinical and basic research.

Our goal is to propose and develop new therapeutic strategies, including personalized approaches to each individual's disease.

It is therefore essential that researchers also focus their studies on metabolic changes caused by pathogenic bacteria, in order to develop new therapeutic strategies against legionellosis and other diseases linked to intracellular bacteria.»

The objectives of the muscular disease team are to explore and validate the potential of human and dog pluripotent stem cells — human Embryonic Stem (hES) cells and induced Pluripotent Stem (iPS) cells — and their differentiated progenies to design new therapeutic strategies for muscles diseases.

«The long - term goal is to develop new therapeutic strategies based on the molecular host response that not only help to improve survival of patients with severe infections but also could limit the use of antibiotics,» said Henrik Thorlacius, M.D., Ph.D., a researcher involved in the work from the Department of Surgery at Skane University Hospital at Lund University in Lund, Sweden.

«A better understanding of the brain region and cell type - specific binding targets of Hnrnph1 will tell us more about the function of this gene and possibly identify new therapeutic strategies for minimizing risk and treating psychostimulant addiction — a disorder for which there is currently no FDA - approved drug,» explained corresponding author Camron Bryant, PhD, assistant professor of Pharmacology and Experimental Therapeutics & Psychiatry at BUSM.

Tonks is obtaining very promising results aimed at designing new therapeutic strategies targeting these enzymes, and is working closely with breast cancer clinicians to move forward on a clinical trial.

Examination of such mechanisms by which the brain naturally protects itself may lead to more selective cellular and molecular targets, as well as new therapeutic strategies against brain disease.

«Researchers discover a potential new therapeutic strategy for pancreatic cancer: Researches have have isolated a subpopulation of cancer - associated fibroblasts, which promote tumour growth.

Since then he has continued to investigate new strategies to overcome the major hurdles to safe and effective gene transfer, translate then into new therapeutic strategies for genetic disease and cancer, and allowed new insights into hematopoietic stem cell function, induction of immunological tolerance and tumor angiogenesis.

Katerina Akassoglou, PhD, and her research team have uncovered a promising new therapeutic strategy for treating disabling neurological diseases.

Consequently we highlight and investigate new therapeutic strategies.

Currently, as a principal investigator, because of the overlap of CAA and AD, I have used my background knowledge of the cerebrovasculature system to study new therapeutic strategies for AD.

A study published June 1 by Nature Communications reports scientists identify a new gene essential to this process, shedding new light on possible new therapeutic strategies.

«This finding,» Villanueva said «opens the door to developing new biomarkers and new therapeutic strategies exploiting these characteristics of exosomes in breast tumors, and other tumors such as ovarian and endometrial cancer among others.»

«The findings help us to shed light on developing new therapeutic strategies by targeting or pharmacologically upregulating MyD88 short production,» Li said.

As Carmen Guerra, one of the lead researchers, and Magdolna Djurec, first author of the work, explain «there are now many groups looking into the relationship of the stroma and tumour growth, with the hope of finding new therapeutic strategies.

In this case, zebrafish were critical for advancing our understanding of Jagged function in the liver, allowing us to devise new therapeutic strategies for Alagille Syndrome.»

We utilize a combination of structural biology, biochemistry, and cell biology to determine the unique and critical protein and nucleic acid components in these pathways that can be targeted for new therapeutic strategies aimed at drug resistant infections.

His studies may kindle new therapeutic strategies relevant to a broad range of cancers.

Better knowledge on protective mechanisms of one sex, for cardiometabolic and renal complications and psychological disorders, could help to establish new therapeutic strategies for both sexes.

«To truly understand a complex disease like Huntington's, we must also look to the brain's naturally evolved defense mechanisms, which as we've shown here could represent an entirely new therapeutic strategy.»

This network funds pilot studies to expedite collaboration between the two groups, conduct model organism - based functional studies of disease gene variants, and develop new therapeutic strategies using model organisms.

To better understand UTIs and potentially offer new therapeutic strategies, a team of researchers analyzed 43 strains of E. coli sampled from 14 women with recurrent UTIs, and found that infection depends on both individual host susceptibility and how the bacteria express their genes.

Ovarian cancer is a silent disease with a poor prognosis that urgently requires new therapeutic strategies.

«The understanding of the brain we can get from such a system will hopefully lead to new therapeutic strategies involving neural stimulation of the brain, which we can implement with this new neurotechnology.»

In light of these exciting results, it's not surprising that the team proposed quercetin as a «potential new therapeutic strategy against pancreatic cancer.»

With these «disease - specific» iPS cells in hand, researchers can learn more about how such diseases develop and hopefully identify new therapeutic strategies.

Now, researchers may finally understand an important mechanism that keeps this friendly truce intact — a finding that may lead to the development of new therapeutic strategies for such chronic diseases.

The next objective of the researchers is to decode the action mechanism of TREX2 in the development and maintenance of psoriasis, so as to design new therapeutic strategies for the treatment of this disease.

Reporting their study data Sept. 22 in the journal Immunity, scientists at Cincinnati Children's Hospital Medical Center say their findings in mice should also provide insights into new therapeutic strategies and diagnostics for food allergies and anaphylactic shock triggered by the immune antibody IgE (immunoglobulin E).

Katerina Akassoglou, PhD, and her research team at the Gladstone Institutes uncovered a promising new therapeutic strategy.

Development of advanced preclinical models are needed to further elucidate the complex mechanisms underlying asthma exacerbation and investigate new therapeutic strategies.

It is also important to take this into account when developing new therapeutic strategies, for example by combining a synapse restoring approach with one that would remove the Tau aggregate at the synapse.»

Combining DM1 - specific biomarkers with a large - scale screening should provide more insights into the development of new therapeutic strategies for DM1.

«This could lead to a new therapeutic strategy for treating type 2 diabetes,» says Stanford, whose team believes that the drug could lead to fewer people with adult - onset diabetes becoming dependent on insulin injections.

According to Srikumar Chellappan, Ph.D., chair of the Department of Tumor Biology at Moffitt, «we expect that this study will lead to new therapeutic strategies to combat cancer metastasis.

There is an urgent need to develop new therapeutic strategies to combat refractory T - ALL and our study uncovers a way to enhance the effectiveness of chemotherapy,» said Fukun Guo, PhD, study first author and a researcher in the Division of Experimental Hematology and Cancer Biology at Cincinnati Children's.

«This could lead to a new therapeutic strategy for treating type 2 diabetes,» says Stanford, whose team believes the drug could mean that fewer people become dependent on insulin injections.

The findings point to the possibility of boosting dectin - 1 levels, or otherwise restoring its protective effect, as a new therapeutic strategy against asthma and allergies that are related to dust mites, shrimp or other invertebrate triggers.

«Therefore, the targeting of Runx2 expression in multiple myeloma cells may represent a new therapeutic strategy for the treatment of aggressive multiple myeloma.»

«Gene variants modifying Huntington's symptom onset may lead to new therapeutic strategies: Genome - wide association analysis identifies sites associated with earlier - or later - than - expected symptom appearance in human patients.»

The research, led by researchers from the Department of Pathology and Experimental Therapeutics of the Faculty of Medicine and Health Sciences of the University of Barcelona and the Bellvitge Biomedical Research Institute (IDIBELL), contributes to increase the knowledge about this complex and multi-factor inflammatory disease and opens doors to the development of new therapeutic strategies.

In addition, the results of the study have initiated a new therapeutic strategy based on the inhibition of the P45 - IKKα enzyme, a protein that is essential in the case of BRAF mutated tumours, for tumour progression.

With their specific interest in the JAM - C marker, the Geneva team has laid the foundation for a new therapeutic strategy against lymphoma.