Sentences with phrase «normal karyotype»
A "normal karyotype" refers to the complete set of chromosomes in a person's cells, which is typically organized and structured without any abnormalities or genetic disorders. Full definition
Cells with normal karyotype were injected into blastocysts isolated from C57BL / 6 mice.
elifesciences.org
Upon microcarrier dissolution and cell release, the cells maintained functionality by exhibiting the correct phenotype, normal karyotype, and ability to differentiate into multiple cell lineages.
Critically, the expanded lines maintain a normal karyotype, rendering the cells suitable for further investigation and use in screening and disease modeling.
FLT3 mutations are more common in patients with normal karyotype and appear to be associated with a higher rate of relapse after conventional chemotherapy.
Several iPSC lineages were established from independent infections and mechanically expanded for at least 20 passages while maintaining a normal karyotype (data not shown).
We confirmed that all three clones had a normal karyotype and contained the modification based on direct sequencing of the region containing the insertion (Figure S1 and unpublished data).
Microarray analysis, the researchers found, revealed genetic conditions in 2.5 % of the pregnancies with a normal karyotype.
Among cases with sonogram anomalies, microarrays detected genetic problems in 6 % of those with a normal karyotype.
These iPS cells have a normal karyotype, demonstrate telomerase activity and express embryonic stem (ES) cell surface markers.