Sentences with phrase «novel therapeutic approaches»
We aim to identify molecular, circuit, and network mechanisms of cognitive dysfunction and to develop novel therapeutic approaches to restore brain functions in AD and related disorders.
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His research interests include the application of novel therapeutic approaches in the treatment of lung and liver cancer.
Much of this health care burden is caused by late - stage type 2 diabetes, where we do not have effective treatments, so we desperately need new research into novel therapeutic approaches.
He aims to identify molecular, circuit, and network mechanisms of cognitive dysfunction and develop novel therapeutic approaches to restore brain functions in AD.
«Thus, administration of soluble Del - 1 may provide the platform for developing novel therapeutic approaches for neuroinflammatory and demyelinating diseases, especially multiple sclerosis.»
His primary clinical and research focus is dementia, with specific areas of interest including biomarkers to assist in the diagnosis and understanding of disease mechanisms for Alzheimer's and Parkinson's disease, and translational research using novel therapeutic approaches.
Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches
«These studies identify telomeres as a new molecular route implicated in the origin of liver diseases such as cirrhosis, hepatitis or liver cancer, as well as novel therapeutic approaches to prevent and combat them,» concluded the researchers.
«The mechanisms by which circadian rhythms are maintained and the cross talk with metabolic signaling are just beginning to be elucidated,» she says, but they should lead to novel therapeutic approaches in the years ahead.
«At the same time, as the human ZNF217 is associated with poor survival in a variety of cancers, understanding how this protein operates in physiological conditions may help to predict cancer risk, achieve earlier diagnosis and provide novel therapeutic approaches.»
In addition, we employ high throughput screening (HTS), cheminformatics, and medicinal chemistry of novel small molecule reagents that aid in validating novel therapeutic approaches and in understanding the biology of signaling in the central nervous system.
Koo and colleagues are now working on novel therapeutic approaches for targeted interventions, which can be potentially developed for clinical use.
The George lab is currently performing preclinical studies for the future development of novel therapeutic approaches including Deep Brain Stimulation, Optogenetics, Chemogenetics and Precision medicine.
Dr. Rubin's research represents an important achievement as it opens opportunities to discover novel therapeutic approaches for the disease.
«Cambridge has been the best place to do my research due to the incredible concentration of scientists who pursue novel therapeutic approaches using cutting - edge technologies,» he says.
Zhang continues to apply his gift for molecular biology and penchant for neuroscience in studying the molecular underpinnings of neuropsychiatric diseases, hoping to identify novel therapeutic approaches.
Daniel J. Rader, M.D. University of Pennsylvania School of Medicine Novel therapeutic approach to atherosclerosis through modulation of HDL metabolism
The goal is to define selective vulnerabilities that can guide novel therapeutic approaches and biomarker development.
Dr Peter Barlow: «Dr Peter Barlow is funded by a grant from the Chief Scientist Office (Scotland) on a project investigating novel therapeutic approaches for respiratory viral infections.»
Ideally, identification of mediators of the inflammatory response in AMD will yield novel therapeutic approaches to this common and often severe form of blindness, in the form of either blocking or inducing TLR2 signaling events.
«The findings from this study can potentially be translated into novel therapeutic approaches for cancers that are caused by viral infections,» Gao said.
These tumor suppressor genes are two of the most frequently altered genes in human cancer, and understanding how they function at the molecular level will both refine our fundamental understanding of this disease and suggest novel therapeutic approaches to treat it.
«Targeting such pathways, as for instance the Wnt pathway presented in this study, may result in the creation of novel therapeutic approaches for frontotemporal dementia.»
This study will greatly expand our knowledge of the biological processes within plaques that lead to disease and provide novel therapeutic approaches that aim to achieve long - term oral health by specifically removing cariogenic species and leaving beneficial or harmless populations intact.
Dr. George is working on understanding how alcohol, nicotine and drugs of abuse affect the brain and on the development of novel therapeutic approaches, including new medications.
We rely on high quality basic and translational respiratory science, such as these latest findings, to develop novel therapeutic approaches for the millions of patients suffering from devastating and often fatal respiratory conditions.
Hear the story behind Backstage Capital Headliner Novoron Bioscience, a San Diego - based biotech company developing novel therapeutic approaches to address disorders of the central nervous system.
Therefore, a novel therapeutic approach in inflammatory breast cancer could involve a combination of conventional chemotherapy with small - molecule inhibitors of the Cdk2 cell cycle kinase.
«Our worldwide effort to evaluate this novel therapeutic approach has shown positive results and was safe in patients.»
«Researchers identify protein role in pathway required for Ebola replication: May provide insight into novel therapeutic approaches.»
These findings suggest a novel therapeutic approach to protect the kidney from scarring and provide a compelling rationale to test the use of Wnt secretion inhibitors for the treatment of kidney fibrosis and other progressive scarring disorders.
This could serve as the basis for novel therapeutic approaches.
Researchers at Saarland University working with Anna Katharina Schaadt and departmental head Professor Georg Kerkhoff have now developed a novel therapeutic approach and have examined its efficacy in two studies.
It's possible that TUDCA or another molecule that acts via the described mechanisms could be used as a novel therapeutic approach to keep those at risk for type 1 diabetes disease - free for long periods of time, or could even prevent the disease all together.»
«We have raised the possibility for developing novel therapeutic approaches,» Bhattacharyya said.
However, coreceptor - specific ZFNs represent a novel therapeutic approach to recapitulate this success via autologous transplantation of gene - modified hematopoietic stem cells and mature CD4 + T cells.
As this regulation mechanism mediated by the immune system also plays an important role in other diseases such as leukemia, these findings could lead to novel therapeutic approaches.
The team of neuropsychologists at Saarbrücken have developed a novel therapeutic approach that has now been tested in two separate studies.
The Barczak laboratory is interested in understanding the TB host - pathogen interface as a means to developing novel therapeutic approaches to treating TB.
Novel therapeutic approaches for the prevention of lethal arrhythmias and heart failure progression
The authors concluded that although the studies included in this review provided important information, double - blinded, sham - controlled phase II and phase III clinical trials with larger sample sizes are needed to validate this novel therapeutic approach.
The Zhang laboratory studies ovarian cancer biology with the goal of developing novel therapeutic approaches to combat the disease with precision.
Together with our collaborators in other UT Health San Antonio departments, we are currently investigating if prohibiting the accumulation of DNA abnormalities can be used as a novel therapeutic approach for treating MDS.
These new understandings may lead to a novel therapeutic approach that improves muscle function in older individuals and in those with chronic diseases.
Therefore, novel therapeutic approaches might be in order.
Carcinomas arise from epithelial cells, and tumor progression involves a loss of polarity, so an understanding of cell polarity is important in the identification of novel therapeutic approaches to cancer.
The development of new transgenic mice carrying selected human molecular targets that are good candidates for novel therapeutic approaches is one of our major research activities.