Sentences with phrase «of bone marrow»

For their discoveries of molecules that regulate the growth and differentiation of bone marrow cells in health and disease.

Treatment consists of a bone marrow transplant with total body radiation treatments.

To confirm the diagnosis, a sample of bone marrow, obtained by needle aspiration or needle biopsy, may be required to confirm the diagnosis.

One difference is the type of bone marrow; chicken is more red marrow, while beef is more yellow marrow.

However, various forms of the bone marrow disease leukemia are caused by a malignant transformation of exactly these blood stem cells.

The use of bone marrow increased from 20 percent in countries with low and low - middle incomes to 50 percent with high - middle incomes to 64 percent with high incomes.

The chief function of bone marrow is to produce blood cells.

The average adult has approximately six pounds of bone marrow.

They are squeezed out of the bone marrow too early and are not functional.

I just spent the past two and a half years taking care of my mother, who died of bone marrow cancer at a young age.

If the cat's immune response failed to initially fight the virus, a later stage characterized by persistent infection of the bone marrow and other tissue is developed.

The condition that results when the immune cells of a transplant (usually of bone marrow) from a donor attack the tissues of the person receiving the transplant.

One of the functions of bone marrow is to produce the cells of the immune system that fight off infection.

Researchers at Dana - Farber / Boston Children's Cancer and Blood Disorders Center report promising outcomes from a clinical trial with patients with a rare form of bone marrow failure who received a hematopoietic stem cell transplant (HSCT) after pre-treatment with immunosuppressive drugs only.

However, the role of bone marrow transplantation in the treatment of children with other forms of cancer, blood diseases, and genetic disorders of immunology and metabolism has increased dramatically in the last few years.

«Umbilical cord blood contains an enriched population of bone marrow stem cells,» says Daniel Weisdorf, director of the Adult Blood and Marrow Transplant Program at the university.

Researchers at Washington University School of Medicine in St. Louis have developed a nanotherapy that is effective in treating mice with multiple myeloma, a cancer of bone marrow immune cells.

Furthermore, the study authors found that the action of ATG16L1 protected tissue against the spikes in TNF - alpha levels seen in graft - versus - host disease, a frequently occurring complication of bone marrow transplants in blood cancer patients.

The Nefedova laboratory focuses on understanding the role of bone marrow microenvironment in regulation of tumor progression and therapy resistance.

In the last couple of years, it has been recognized that after long term treatment (many moths to a year or more) with metronomic chlorambucil, that chronic suppression of the bone marrow can occur resulting in prolonged low platelet or white blood cell counts.

Supplying MSCs as early as possible, Semler thought, might give a fetus a better chance to build healthy bone, without the side effects of a bone marrow transplant after birth.

The picture shows a stroma cell of the bone marrow of a mouse secreting the messenger CTGF (red).

Rubén Ferrer (Bornhäuser, TUD)-- «Functional analysis of the bone marrow microenvironment in myelodysplastic syndrome: targeting the disease niche» (2013)

Complete obliteration of bone marrow progenitor cells by chemotherapy or bone marrow cancer can result in bone marrow failure and death.

A disease of bone marrow failure, the condition can cause skeletal deformities and increases cancer and anemia susceptibility.

«Research suggests new way to treat inflammatory gut disease and prevent rejection of bone marrow transplants.»

In a study published in Nature Communications, the investigators report that hyperglycemic mice (or mice with type 2 diabetes) have a 24-fold higher accumulation of succinate, an intermediate metabolite, in the metabolic pathways of their bone marrow stromal cells.

In humans, a comparison of bone marrow from 14 normal bone marrow donors, 35 multiple myeloma patients and 11 patients with a noncancerous condition called monoclonal gammopathy of undetermined significance (MGUS) showed that Runx2 levels were significantly higher in the multiple myeloma cells.

Researchers have long known that a follow - up infusion of bone marrow cells from the same donor eases the transition, but they haven't known why.

Dr. Carlesso's group has pioneered the study of bone marrow responses during acute infection.

To devise a potential new therapy, the investigators engineered a population of bone marrow derived mesenchymal stem cells loaded with oncolytic herpes simplex virus (oHSV), which specifically kills dividing cancer cells while sparing normal cells.

That could help recipients of bone marrow transplants.

About 50 - 70 percent of bone marrow transplant patients will acquire GVHD.

Unrelated donor registries should provide information on the necessity of bone marrow donation for patients with bone marrow failure.»

Mouse models of bone marrow transplantation.

In 2004 she transferred to the NIDCR and heads the Adult Stem Cell Section to study the biology of bone marrow derived stem cells.

This may be because of poor health and especially atherosclerosis have affected the health of the bone marrow, although people with recent heart attacks or other severe disease were excluded from the study, Quyyumi says.

The first reports that gene - editing of bone marrow stem cells in monkeys infected with a variant of simian immunodeficiency virus (SIV) significantly reduces the number of dormant «viral reservoirs» that pose a risk of reactivation.

In it, they asked themselves, â $ œWhy now?â $ After all, their papers on the colony - assay model of cells from the mouse spleen â $» which described for the first time the hematopoietic stem cell of the bone marrow as a cell that is capable of both self - renewal and differentiation â $» are more than 40 years old.

Importance of recruitment of bone marrow - derived CXCR4 + cells in post-infarct cardiac repair mediated by G - CSF.

To determine a possible impact of the allograft on mixed chimerism, we measured the levels of bone marrow mixed chimerism 40 days post cardiac graft transplantation.

B Cell Formula contains fractions of bone marrow and glandular extract that works well with T Cell Formula.

The therapeutic potential of bone marrow transplantation (BMT) relies on the graft - versus - leukemia (GVL) effect, which is closely associated with graft - versus - host disease (GVHD), the major cause of morbidity and mortality after BMT (1 — 4).

the removal and evaluation of bone marrow cells to determine if the cells are normal, if cancer has spread to the bone marrow or if there is a problem with blood cell production.

University researchers hope to improve the odds of surviving acute myeloid leukemia by loading a promising compound into nanoparticles that will target the inner recesses of bone marrow where leukemia stem cells lurk.

They will load the drug into nanoparticles that will target the inner recesses of bone marrow where leukemia stem cells lurk.