Sentences with phrase «of cell differentiation»

The localized delivery technique provides spatial control of cell differentiation within the cultures, potentially enabling the creation of complex three - dimensional tissues.

Such research on the basic processes of cell differentiation holds out the promise of dramatic new medical interventions and cures.

The microparticle technique, which was demonstrated in pluripotent mouse embryonic cells, also offers better control over the kinetics of cell differentiation by delivering molecules that can either promote or inhibit the process.

He worked with chemist Olaf Runquist to develop mathematical models of cell differentiation based on colon cancer samples from collaborator Bruce Boman, a professor at the University of Delaware.

For biologists, 14 days marks the start of cell differentiation: before this, the embryo has no precursors of nerves or blood, so it can not possibly know or experience anything.

Failure of this regulation not only impairs the process of development, but also contributes to the reversal of cell differentiation and the uncontrolled cell growth that are the hallmarks of cancer.

Seeking fresh sources, they looked for cells that express the gene neurogenin 3, a potential sign of cell differentiation because it is the first gene to only switch on in pancreatic islets during embryonic development.

One of the most attractive features of this model is the presence of the thermolabile large T antigen, which allows the user to regulate the level of cell differentiation.

Fetal development in mammals is becoming well understood in terms of the causes of cell differentiation and gene activation.

We have discovered that the deregulation of microRNAs following chromosome instability is responsible for the acquisition of tumor related phenotypes and the induction of a metastable state of cell differentiation in which epithelial cells respond to a senescence microenvironment by engaging in transitions deemed to be important for different steps in the metastatic progression of carcinomas.

In addition to p53, there are other transcriptional activatory mechanisms that are not well understood for the most part and which operate in response to mitogenic stimulation (11, 12), transforming growth factor - β (13, 14, 15), and aberrant oncogenic signals (16, 17) or during a number of cell differentiation processes (18, 19).

1964 * Frederick Campion Steward for his many important contributions to the knowledge of cell differentiation and specific growth factors

Affiliations Key Laboratory of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences / Shanghai Jiao Tong University School of Medicine, Shanghai, China, Shanghai Stem Cell Institute, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Dr. Olson's laboratory studies muscle cells as a model for understanding how embryonic cells adopt specific fates and how programs of cell differentiation and morphogenesis are controlled during development.

By affecting the rate of cell differentiation and gene expression, thyroid hormones regulate the growth and migration of neurons, including synaptic development and myelin formation in specific brain regions.

The microparticles could also provide better control over the kinetics of cell differentiation.

We have a longstanding interest in understanding gene expression regulation, and in our wetlab at the Sanger Institute use mouse T helper cells as a model of cell differentiation.

This screening approach revealed several microRNA molecules that induce the process of cell differentiation, and those are key to developing new drugs.