The process uses a computational model to generate predictions about the dynamics
of cell receptors in different cellular compartments.
«
Activation of these cell receptors appear to prevent brain cells from cleaning out the trash — the toxic buildup of proteins, such as alpha - synuclein, tau and amyloid, common in neurodegenerative diseases,» says the study's senior author, neurologist Charbel Moussa, MBBS, PhD, director of Georgetown's Laboratory for Dementia and Parkinsonism, and scientific and clinical research director of the GUMC Translational Neurotherapeutics Program.
«Activation
of these cell receptors appear to prevent brain cells from cleaning out the trash — the toxic buildup of proteins, such as alpha - synuclein, tau and amyloid, common in neurodegenerative diseases,» says the study's senior author, Charbel Moussa, MBBS, PhD, director of Georgetown's Laboratory for Dementia and Parkinsonism, and scientific and clinical research director of the GUMC Translational Neurotherapeutics Program.
The Harvard School of Public Health explains that omegas — 3 and — 9 «are an integral part of cell membranes throughout the body and affect the
function of the cell receptors in these membranes.
Monk also said that Gpr56 belongs to a large
class of cell receptors that are common targets for many commercially available drugs, making the protein attractive for further research.
Nyce and his colleague James Metzger, a clinician at East Carolina University, have devised a way to reduce the sensitivity of lung cells to adenosine by interfering with the
production of cell receptors that bind it.
When the researchers modeled the effects in mice, they found it strengthened the connections between neurons that make learning possible — what is known as synaptic plasticity — by increasing the
action of a cell receptor critical to forming memories.
If cortisol is bound to a greater
number of cell receptors, protein breakdown is increased; however, if anabolic hormones such as testosterone and GH occupy a greater number of receptors, protein is enhanced.
explains that omegas — 3 and — 9 «are an integral part of cell membranes throughout the body and affect the
function of the cell receptors in these membranes.