Sentences with phrase «of cellular aging»

Despite the pressing need to alleviate this problem, our understanding into the mechanisms of cellular aging and how these mechanisms are coupled to the initiation of various disease states is very limited.

The little tips of chromosomes get shorter every time a cell divides, and this shortening is a mark of cellular aging.

The overall goal will be to test this improved targeting technology so that it can be optimally refined for use in rescuing mutated mitochondrial DNA, and thus prevent and cure what may be one of the major causes of cellular aging.

Pulmonary fibrosis can possibly be attributed to a kind of cellular aging process, which is called senescence.

Telomeres are the protective tips found at the end of each DNA strand and are indicative of cellular aging.

Stunted Telomeres Telomere shortening is now considered a biomarker of cellular aging, and more evidence suggests that these tiny fragments of DNA may be one of the culprits behind age - related decline.

Brazilian scientists from the D'Or Institute of Research and Education (IDOR) and the Federal University of Minas Gerais (UFMG) found that ADHD kids and their mothers are more likely to have shorter telomeres, a hallmark of cellular aging, which is associated with increased risk for chronic diseases and conditions like diabetes, obesity and cancer.

New research indicates that people who had more infections as babies harbor a key marker of cellular aging as young adults: the protective stretches of DNA which «cap» the ends of their chromosomes are shorter than in adults who were healthier as infants.

If non-disruptive ways to accelerate lipofuscin removal can be found, our results suggest that therapeutic reversal of this most universal manifestation of cellular ageing may be possible. - link

Elizabeth B. Moloney, PhD, is a post-doctoral research fellow at the Neuroregeneration Research Institute at McLean Hospital, where she is involved in developing both in vitro and in vivo approaches for understanding the role of lysosomal function in the pathophysiology of cellular aging and...

Anyone who meditates regularly will speak of the myriad benefits it provides — from reducing anxiety to re-centering oneself — but some of the most intriguing research reveals that there is a correlation between meditation and the reduction of cellular aging.

While the consumption of whole plant foods has been associated with longer protective telomeres, the tips on each of our chromosomes that keep our DNA from unraveling and fraying, in contrast, consuming refined grains, soda, dairy, and meat, including fish, has been linked to shortened telomeres, a sign of cellular aging.

In fact, the degree of telomere shortening was equivalent to an additional 4.6 years of cellular aging.

Proteins called sirtuins are major regulators of cellular aging because they influence fundamental functions such as DNA repair and inflammatory responses.

However, this is not necessarily the mechanism that allows blind mole rats to resist cancer, points out Jerry Shay, who studies mechanisms of cellular ageing and death at the University of Texas Southwestern Medical Center in Dallas.

«More broadly, it suggests that accumulated alterations in the structure of heterochromatin may be a major underlying cause of cellular aging.

Red wine contains resveratrol, a compound that has been found to slow down the process of cellular aging and inhibit the growth of oral cancer cells.

Aging in yeast is accompanied by nucleolar enlargement and fragmentation, suggesting a mechanism of cellular aging that may be related to nucleolar structure.