The researchers found that these electric currents were much weaker in eyes from all three
strains of diabetic mice than in healthy mice.
Implanting the HydrogeLEDs into the
skin of diabetic mice allowed Shao and colleagues to administer insulin doses remotely through a smartphone application.
This phenomenon coincided with a reduction in the number of infiltrating dendritic cells in the wounded
corneas of diabetic mice, leading to the conclusion that sensory neuropathy is related to this decline in the dendritic cell population in the diabetic cornea.
The activity of genes involved in cholesterol production in the hypothalamus — an area involved in the brain's energy maintenance — was reduced by 25 per cent in both
groups of diabetic mice.
In the
livers of diabetic mice, interleukin - 6 reduces production of glucose, so that overall blood sugar is lowered.
In people with diabetes, beta cells don't function well, but Melton and his team were able to use the new beta cells to improve the glucose
state of diabetic mice.
As a result, diabetes was reversed in 60
percent of the diabetic mice that received the experimental therapy, while none of the control mice recovered from their disease, said Miao Wang, M.D., Ph.D., first author of the study and a postdoctoral research fellow in Zeng's lab.
A Canadian study, developed by researchers E Arany, B Strutt, et al, from Lawson Health Research Institute, St. Joseph's Health Care, London, Ontario, investigated whether supplements of the amino acid taurine would inhibit the development of diabetes in the
offspring of diabetic mice.
A few hundred transparent microcapsules filled with approximately 10 million of the cells each, were then implanted under the
skin of diabetic mice.