Sentences with phrase «of key genes»

Now researchers have found that the evolution of a key gene involved in brain development may help explain the disparity.

Researchers have used genome editing technology to reveal the role of a key gene in human embryos in the first few days of development.

Most of the key genes that the researchers identified were already known to be important in human lymphoma.

We have identified several of the key genes and molecular genetic mechanisms that have contributed to such diversity.

Scientists have for the first time shown how the disruption of a key gene involved in mental illness impacts on the brain.

«What we observed is that the levels of many miRNAs change significantly throughout the 48 - hour period following a blood meal, indicating that these miRNAs, in turn, may be establishing significant changes in expression of key genes during this time in the fat body,» said Fedor V. Karginov, an assistant professor of cell biology and neuroscience, who co-led the research team along with Alexander S. Raikhel, a distinguished professor of entomology at UC Riverside.

The susceptibility of German shepherds to chronic diarrhoea is not due to a failure of transcription of key genes encoding molecules involved in mucosal IgA secretion In collaboration with scientists at the University of Bristol, UK, WALTHAM investigated a potential cause of the susceptibility of German shepherd dogs to chronic diarrhoea (Peters et al. 2005).

Niakan, who works at the Francis Crick Institute in London, applied for permission to use the technique in studies to better understand the role of key genes during the first few days of human embryo development.

Showing that the susceptibility of German shepherds to chronic diarrhoea is not due to a failure of transcription of key genes encoding molecules involved in mucosal IgA secretion.

In recent years, clock researchers have uncovered some of the gears and springs that keep this circadian timepiece running, largely by identifying a handful of key genes in organisms from bread mold to mice.

Nusinersen is an antisense therapy that restores cells» ability to make a protein that is vital to the survival of motor neurons and that is largely absent in children with the disease, who carry a mutated form of the key gene that produces this protein.

Matthew Dyson, research assistant professor of obstetrics and gynecology at Northwestern University Feinberg School of Medicine and and Serdar Bulun, MD, chair of obstetrics and gynecology at Feinberg and Northwestern Memorial Hospital, also identified a novel role for a family of key gene regulators in the uterus.

«It's really cool that they can pinpoint the acquisition of key genes that allow the movement of this bacteria into fleas,» says evolutionary geneticist Hendrik Poinar of McMaster University in Hamilton, Canada, who was not involved with the study.

Sets of key genes that control growth and maturity were found to reach a more advanced profile of activity on the left side than the right.

With the acquisition of a number of key genes and lipids from a bacterial symbiont, it would be possible for Loki - type cells to evolve a primitive membrane trafficking machinery and compartmentalization.»

If both parents have cystic fibrosis, for example, any offspring would inherit the disease — it's a so - called autosomal recessive disorder, which means an affected person has mutations in both copies of the key gene, and all children of an affected couple would also carry double mutations.

There have been few concrete reports of the genes involved in hybrid vigor, but based on this research, one of the key genes for hybrid vigor has been clarified.

It is likely that inhibition of DNMT and histone deacetylase can also prevent the hypermethylation and silencing of these key genes and, therefore, this inhibition would contribute to the prevention of carcinogenesis.

Although LGDs can impair the function of key genes, and in this way have a deleterious impact on health, this is not always the case.

This technology is based on differential expression of key gene transcript variants (isoform - level gene expression) and was originally tested on a vast collection of glioblastoma samples made available by the University of Pennsylvania.

This study generated more than 5 million datapoints, information that led to the identification of key genes indicative of responsiveness to glucocorticoids.

Now, Whitehead Institute researchers present the first evidence that DNA structure does indeed have such effects — in this case finding a link between chromosome structure and the expression and repression of key genes.

This flexibility is interesting because it shows that our nervous system can adapt despite the loss of a key gene», continues Klas Kullander.

Rather it is the definition of those key genes that encode the targets for intervention in disease.

Fortunately, like most animals including humans, monarchs possess an internal clock based on the rhythmic expression of key genes.

This study confirmed that the susceptibility of German shepherds to chronic diarrhoea is not a result of simple failure of transcription of the key genes that encode molecules involved in mucosal IgA secretion (Peters et al. 2005).

To further investigate additional similarities between hNSCs and hESCs at the transcriptional level, we analyzed the expression of key genes involved in hESC self - renewal and pluripotency utilizing semi-quantitative RT - PCR analysis.

Rhythmic expression of key genes is essential for maintaining proper timekeeping of the body's clock.

The tip of this ear of corn is growing abnormally, but provided scientists with information about how to tweak expression of a key gene to boost yield.

They don't yet know which receptors irisin interacts with, but they suggest it prompts the production of proteins that in turn increase the expression of key genes — those that drive immature cells to differentiate into osteoblasts, which synthesize new bone.

Examining the muscles of insulin - resistant mice, the scientists found similar boost in the expression of those key genes.

Some of the key genes produce waterborne pheromones, used by the barnacles to attract each other, which allows them to attach to surfaces close to each other where they will be able to mate.

However, if the purpose of such a scan is to identify candidate genes, then — as with single - gene studies — more detailed follow - up and functional validation of at least some of the key genes of interest are necessary to shore up the evidence.