Sentences with phrase «of nucleic acids»

I have followed Polanyi's contention that there are organizational principles operative in the universe which formatively influence the specific sequences of nucleic acids in DNA, and with Sheldrake I have postulated the existence of morphogenetic fields which canalize the processes of growth and development in organisms.

The shortest chain of nucleic acids capable of replicating itself consists of only 6 molecules.

This chemically enhanced X-ray technique revealed that DNA was composed of two complementary strands of nucleic acids linked by chemical bonds on a ladder - like chain.

«Successful detection of nucleic acids in Martian permafrost samples would provide unambiguous evidence of life on another world,» says Dr Goordial.

Magnesium is an essential element for general health and biological functions such as protein production, glucose metabolism and the synthesis of nucleic acids like DNA.

His new lab will focus on developing different types of nucleic acid delivery platforms for gene therapies.

The CRISPR system is made up of two components: a protein called Cas9 and a guide RNA, a string of nucleic acid molecules with a certain genetic code.

In their report receiving advance online release in Nature, the investigators describe evolved versions of the DNA - cutting Cas9 enzyme that are able to recognize a different range of nucleic acid sequences than is possible with the naturally occurring form of Cas9 that has been used to date.

Nucleotides, the building blocks of nucleic acids like DNA and RNA, are produced from hydrolyzed yeast.

Genetic and genomic analysis of nucleic acids from environmental samples has helped transform our perception of the subsurface as a major reservoir of microbial novelty.

DNA (DeoxyriboNucleic Acid) a molecule composed of two chains of nucleic acid bases held together by hydrogen bonds in a pattern resembling a flexible twisted ladder.

While there, he worked under Aaron Klug, winner of the Nobel Prize in 1982 for crystallographic electron microscopy and for solving the structures of nucleic acid complexes.

Another nutrient in ginger is B9, also known as folate, which is critical in the metabolism of nucleic acid precursors and several amino acids.

Bacterial microbes face a never - ending onslaught from viruses and invasive snippets of nucleic acid known as plasmids.

An HPV test, in which doctors test a cervicovaginal specimen for the presence of the nucleic acids of carcinogenic types of HPV, is more sensitive than the Pap test (a microscopic examination of exfoliated cells) for detection of precancers.

This separation of nucleic acid strands is brought about by interaction with a set of proteins loops in a strand / loop network.

ANA (amyloid nucleic acid) consists of nucleic acids attached to amyloid proteins, infamous for their role in Alzheimer's disease.

And with nucleic acids, he investigated the effects of pH and especially temperature on the native properties of DNA, initiating the technique of thermal melting analysis of nucleic acid molecules and thereby contributing to an understanding of their thermodynamics and the conformational differences between duplex DNA and single - stranded RNA (5, 6).

Chemical modifications of nucleic acids constitute the Epigenome (DNA) and the Epitranscriptome (RNA), which regulate the activity of the Genome.

And a new prototype device can display a fluorescent letter in the presence of nucleic acid sequences from the Ebola virus or the closely - related Marburg virus: «E» for Ebola or «M» for Marburg.

Manuscripts describing BioGPS have been published in the database issues of Nucleic Acid Research in 2016 and 2013, as well as in Genome Biology.

MicroRNAs are very short bits of nucleic acid — the material of DNA and RNA — that can bind to messenger RNAs that code for protein.

«We identified a set of novel microRNAs that are potent inducers of neuroblastoma cell differentiation and found that mimics (synthetic fragments of nucleic acid used to raise microRNA levels in cells) of some of the identified microRNAs are much more potent in inducing neuroblastoma cell differentiation than the current differentiation treatments.

He is currently a Human Frontier Science Program (HFSP) postdoctoral fellow in the laboratory of Professor Chuan He at the University of Chicago, Illinois, USA, where he develops novel chemistries for the study of nucleic acid modifications.

Characterization of the nucleic acid binding region of adenovirus DNA binding protein by partial proteolysis and photochemical cross-linking

His research has involved studies of the expression of human genes in normal and diseased states and the detection of nucleic acid alterations.

One way to identify microbes is a microarray containing strands of nucleic acids complementary to DNA or RNA in different viruses.

One way to shut down the communication link is through a snippet of RNA called «antisense» — which binds to the messenger RNA (a «sense» - making strip of nucleic acids) that is transcribed by a given stretch of DNA.

This task involves analyzing no less than 3 billion pairs of nucleic acids.

Here we can say that what the molecular biologists have done is to develop a model of the cell which behaves very much like a classical man - made machine, or an automaton, but one in which the «secret of heredity» is found in the normal chemistry of nucleic acids and enzymes.

Research on antimetabolites of nucleic acid purines led to drugs for the treatment of acute leukemia (6 - mercaptopurine and thioguanine), gout and hyperuricemia (allopurinol), and herpesvirus infections (acyclovir), and for the prevention of organ transplant rejection (azathioprine).

Found in amino acids, the building blocks of proteins; an essential part of the nucleic acids that constitute DNA.

Dr Ciro Chiappini, first author of the study from the Department of Materials, added: «If we can harness the power of nucleic acids and prompt them to carry out specific tasks, it will give us a way to regenerate lost function.

I had decided to pursue a Ph.D. studying the physical properties of nucleic acids and had won admission to UD, with a teaching assistantship.

Most of the prize money will go to new research and a company party, but CureVac also plans to use some of it to build an exhibit honoring Friedrich Miescher, a 19th century Swiss scientist whose discovery of nucleic acids isn't widely known.

The mutant deficient of uracil — a basic compound of nucleic acid — appeared to have lost the ability to maintain symbiosis with the model organism sea anemone.

For tumors to grow and spread, cancer cells must make larger than normal amounts of nucleic acids and protein, so they can replicate themselves.

The rules of nucleic acid base - pairing have been used to construct nanoscale architectures and organize biomolecules, but little has been done to apply this technology in vivo.

Department of Nucleic Acids Research, Genetic Engineering and Biotechnology Research Institute, City for Scientific Research and Technology Applications, Borg El - Arab, Post Office Box 21934, Alexandria, Egypt.

«This lab knows how to look at and detect these types of molecules,» says Patrick A. Limbach, a chemist who studies mass spectrometry of nucleic acids at the University of Cincinnati.

The technique introduces modified segments of nucleic acid from the gene that produces the nicotine demethylase enzyme.

Investigations of how short chains of nucleic acids replicate themselves in vitro have even provided clues to primitive genetic codes for translating nucleic acid information into protein information, systems that could have preceded the elaborate machinery of ribosomes and activating enzymes with which cells now manufacture protein.

It is a member of an understudied class of nucleic acids that biologists call long non-coding RNAs (lncRNAs).

The result was several series of nucleic acid duplexes that ranged from having all RNA nucleotides to none at all.

He has more than 12 years experience in directed evolution and engineering of nucleic acid and protein biomolecules.

For each sample type, a standard curve for the TMAdV PCR assay was calculated from 3 PCR replicates at each dilution of nucleic acid extracted from the spiked matrix (data not shown).