Sentences with phrase «of paclitaxel»

Fostamatinib's effect on microtubules seems to increase the stabilizing effect of paclitaxel, even in resistant cells, which in turn may prevent cancer cells from proliferating, says Yu Yu, Ph.D., a postdoctoral fellow at the Johns Hopkins University School of Medicine and co-author of the study.

Instead, Esserman's team encouraged hospitals involved in the trial to use abraxane for patients not enrolled in I - SPY 2, freeing up more of the limited supplies of paclitaxel for trial participants.

Even as he leads a national clinical trial testing a combination of paclitaxel chemotherapy with an experimental agent known as efatutazone, Dr. Smallridge is working with Dr. Copland and researcher Laura Marlow to find an HDAC inhibitor that might offer additional benefit.

Nanotax is the fine particle formulation of paclitaxel mixed with saline, which the body can absorb and tolerate much better without the allergy risk.

Gamma secretase inhibition by BMS - 906024 enhances efficacy of paclitaxel in lung adenocarcinoma.

The drug, known under the brand name Nanotax, is a fine particle reformulation of paclitaxel, the standard treatment for ovarian cancer.

However, finding an alternative when supplies of paclitaxel dried up proved more challenging.

A total of 374 women received the standard chemotherapy treatment of paclitaxel and carboplatin.

The scientists also analyzed tissue from 20 breast cancer patients who had undergone pre-op chemo (12 weeks of paclitaxel and four of doxorubicin and cyclophosphamide).

Cell culture holds the potential for an environmentally friendly, less capital intensive and more reliable method of production that can generate large quantities of paclitaxel and taxane intermediates at costs significantly lower than those of current tree - harvest methods.

Pharmacological characterization of paclitaxel - induced neuropathic pain in rats.

In rodents, administration of paclitaxel causes neuropathic pain that comprises of thermal hyperalgesia and mechanical allodynia, which can be reversed by different analgesic agents.

The effects of paclitaxel, a chemotherapy drug, can be seen on the cellular structures of the skin of a larval zebrafish tail fin.

According to Miguel Ángel Quintela, head of the Unit: «The drug combination of paclitaxel and nintedanib has turned out to be a complete success, given that it is proved to be safe and that the pathologic complete response [rate of complete recovery] was 50 %, which doubles the response compared to patients treated with standard therapy with paclitaxel.»

In 2013, Abraxane (nanoparticle albumin — bound formulation of paclitaxel) was approved in combination with gemcitabine for metastatic pancreatic cancer.

PULLMAN — Washington State University and Exelixis Plant Sciences, Inc., have entered a commercial licensing agreement covering patent rights and biological materials for use of plant cell cultures in the production of paclitaxel and other valuable taxane products used in cancer treatments.

Currently, the supply of paclitaxel or taxane intermediates is largely derived from the harvest of Yew trees.

Effect of paclitaxel / carboplatin salvage chemotherapy in noncutaneous versus cutaneous metastatic melanoma.