Sentences with phrase «of white fat»

A more recent study found that cold applied to human neck fat initiated the conversion [21] of white fat cells into brown ones.

This led in the former to a conversion of white fat into energy - burning brown fat, and in the latter to an enhancement of their anti-inflammatory properties.

The roast should have a moderately thick layer of white fat over the meat.

Both drugs succeeded in turning significant amounts of white fat brown and significantly increasing the amount of energy mice burned when researchers turned down the temperature in their living quarters.

His findings on the role of white fat in bone also have important implications.

Furthermore, he demonstrated that a class of drugs often used in the treatment of diabetes also reduces the harmful effects of white fat cells on bones.

In their recent study, the UCSF team reports the discovery that a class of commonly prescribed Type - 2 diabetes drugs, called TZDs (thiazolidinediones, such as Actos and Avandia), promoted the conversion of white fat cells into brown (in mice and culture dishes) by stabilizing the PRDM16 protein.

When they exposed these mice to the cold, the animals developed far fewer beige fat cells than did normal animals, suggesting that macrophages were key to browning of white fat.

«This study reaches two conclusions: First, Cx43 is necessary for the propagation of nerve signals that lead to beiging of white fat tissue.

Significantly overweight people have a particularly large number of white fat cells but in contrast, they lack brown fat cells.

Around 50 g of white fat stores more than 300 kilocalories of energy.

In mice, this form of lipodystrophy was also characterized by «whitening» of brown fat cells, a loss of white fat, and signs of metabolic syndrome, including insulin resistance, fat tissue inflammation, dyslipidemia (elevated cholesterol and fat), increased resting energy use, and increased markers of cardiovascular disease.

«The discovery of the «brite» fat cell mechanisms and the specific regulatory areas brings us closer to understanding how reprogramming of white fat cells takes place.

When Ribeiro studied the interaction between different - hued fat cells and prostate - tumour cells in the lab, he found that the tumours were more aggressive in the presence of white fat.

The study shows that activating the bile acid receptor TGR5 with molecules that mimic the action of bile acids (so called «mimetics») induces a remodeling of white fat cells into beige fat cells.

Such analyses will improve our understanding of how brown fat cells develop and are regulated in the body — and, potentially, how to transform the precursors of white fat cells into brown fat cells instead, says Dr. Tseng.

A group of researchers at Dana - Farber Cancer Institute and Harvard Medical School, led by Bruce Spiegelman and Pontus Boström, have discovered a hormone that mimics some of the results of a workout by facilitating the transformation of white fat into brown fat.

Whitehead Institute researchers report that 10 long noncoding RNAs (lncRNAs) play a vital role in the regulation of white fat cells.

This finding builds upon a 2015 study presented at the annual meeting of the Biophysical Society, which uncovered another weight loss effect of red chili pepper — it showed the spice transformed the health liability of white fat into the health asset of brown fat.

In addition, if caloric intake is too low for your body's need, brown fat can slow the burning of white fat; this often happens on a low - calorie diet, and when meals are skipped.

Thigh tissue samples revealed greater conversion of white fat into brown fat in the lean members of the group, while the obese had less brown fat conversion, probably due to higher baseline inflammation levels.

Lay brisket flat on your cutting board so that one of the longer sides is closest to you and layer of white fat is facing down.

«What is exciting about our discovery is that low concentrations of TGR5 - selective molecules are sufficient to promote the beiging of white fat - storing cells, thereby bypassing the need to increase the total bile acid pool,» says Laura Velazquez, first - author of the paper.

While white fat ups the risk for heart disease, diabetes and other chronic health problems, brown fat has been found to be actually quite healthful since it helps us burn calories and reduce the amount of white fat in all areas of the body.

As the researchers have shown in various studies on mice, the widespread active ingredient sildenafil or a medication against pulmonary hypertension, for instance, can be used to reduce the number of white fat cells to the benefit of the brown fat cells and thus accelerate fat burning like a turbocharger.

For Styner, two future areas interest her most: the browning of white fat and how much exercise is beneficial?

The research team discovered leptin and insulin interact with proopiomelanocortin (POMC) neurons in the brain's hypothalamus, causing them to send signals through the nervous system promoting the conversion of white fat into brown fat.

The «browning» of white fat cells is thought to be initiated by things like exercise, exposure to cold temperatures, and our sleep hormone melatonin.

Flip the salmon and grill for 2 - 5 minutes (until there is a solid mark) and then turn the salmon 90 degrees and cook another 2 - 5 minutes or until the salmon is firm, is expelling some of the white fat, and just barely darker pink in the middle.

The discovery immediately suggested a new approach for treating obesity: enhancing people's baseline stores of energy - burning brown fat, known as the «browning» of white fat.

The findings, published today in the journal Cell, give new insights into how the brain regulates body fat and may lead to more effective ways to lose weight and prevent obesity by promoting the conversion of white fat to brown fat.

Brown fat protects against the cold (it's also common in animals that hibernate), and researchers have found that mice exposed to cold show a temporary «browning» of some of their white fat.