Sentences with phrase «of young mice»

In 2012, researchers reversed some of the effects of cognitive decline by pumping the blood of young mice into old mice.

The team also joined together 12 pairs of old mice and 10 pairs of young mice, as controls.

As a consequence of the study many hundreds of young mice that would otherwise all have died were saved.

In 2011, these researchers reported that this mixing harmed the brains of young mice getting the geezer's blood.

Using a surgical technique called parabiosis to join the circulatory system of a young mouse with that of an old one, the researchers studied the effects of young blood on elderly cells, and vice versa.

In a study published June 27 in Cell Reports, a team led by Thomas Rando, MD, PhD, professor of neurology and neurological sciences and chief of the Veterans Affairs Palo Alto Health Care System's neurology service, has identified characteristic differences in «histone signatures» between stem cells from the muscles of young mice and old mice.

Researchers at the University of Southern California have developed a prostate cancer vaccine that prevented cancer in 90 percent of young mice genetically predestined to develop the disease.

Temporarily closing a single eye of a young mouse for a few days deprives the visual cortex of normal input, and the neurons» electrophysiological response to visual experience changes.

As in the first study, a group of young mice carrying the human gene APOE4 showed cognitive impairment on the behavioral level — in other words, they showed signs of damage on the level of spatial memory.

The researchers harvested satellite cells from both healthy and injured muscle tissue of young mice and from healthy tissue of old mice; extracted these cells» DNA with the histone coatings intact; and used tagged antibodies targeting the different kinds of marks to find which spots on those histones were flagged with either «stop» or «go» signals.

He and a postdoctoral researcher, Maria Milekic, collected data on 100 offspring of younger mouse dads and another 100 offspring of older dads before they decided the results were correct.

Interrupting their development with antibiotics disturbs the metabolism of young mice and boosts their risk of obesity later on.

The researchers measured NF - κB activation in mouse brains as they aged and noted that, while the protein was barely active in the hypothalamuses of young mice, it became increasingly active as the mice got older.

Comparing 13 month old mice to 3 month old mice, blocking the femoral artery in the hind leg causes all older mice to lose their legs while only about a third of younger mice have to lose their legs.

Using a technique called parabiosis, in which the vascular systems of two mice are surgically connected, Villeda's lab had previously discovered that infusing old mice with the blood of younger mice leads to brain rejuvenation, including improvements in learning and memory, while infusions of old blood cause premature brain aging in young mice.

Karmazin's work with human clients follows studies which showed that injections of young mouse blood plasma had a rejuvenating effect on older mice, including improvements in memory, learning, and the development of brain cells.

Are new blood vessels being formed from existing capillaries or from novel endothelial progenitors present in the vasculature of young mice?

The researchers said the compound also restored the mice's memory to the level of younger mice's.

Researchers have shown that THC in marijuana alters the structure of the brains in older mice to be more like brains of younger mice.

In 2014, highly publicized work in the laboratories of Villeda and Tony Wyss - Coray, PhD, professor of neurology at Stanford, showed that connecting the circulatory system of a young mouse to that of an old mouse could reverse the declines in learning ability that typically emerge as mice age.

The GDF11 protein commonly found in the blood of young mice (the same protein that enhanced neurogenesis in aged mice) and placed in individual older mice was thought to have the same reversal effect on hypertrophy; however, more recent research suggests another molecule besides GDF11 may be at work.

The team also distinguished histone - signature differences between quiescent and active stem cells in the muscles of young mice.

Meanwhile, a protein commonly found in the blood of young mice (and humans) may hold the key to rejuvenating brain cells.

When Bading halved the amount of the enzyme in the brains of young mice, their performance deteriorated to that of typical elderly mice (Nature Neuroscience, DOI: 10.1038 / nn.3151).

Our study suggests otherwise, though, as we found that a certain type of B cell is quite abundant in the ventricles, meninges, and choroid plexus in the brains of young mice.

«We experimentally depleted B cells from the brains of young mice and saw oligodendrocyte numbers drop significantly,» Tanabe adds.

«We were astonished that not only did this improve the mice's performance on the memory tests, but their performance was comparable to that of young mice,» said Dr. Pavlopoulos.

The Science studies linked those mental and health benefits to one particular ingredient found in the blood of young mice.

In fact, in the case of one type of age - related memory loss — again, distinct from Alzheimer's — researchers were able to restore memory function in mice so that it was comparable to that of young mice.

«Something — or some things — in the blood of young mice has the ability to restore mental capabilities in old mice, a new study by Stanford University School of Medicine investigators has found.

Using a surgical technique, the researchers introduced an experimental demyelinating injury in the spinal cord of an old mouse, creating small areas of myelin loss, and then exposed those areas to cells found the blood of a young mouse.

In the 1950s, in a Frankenstein - style process called parabiosis, scientists sewed the circulatory system of a young mouse to that of an old mouse.

Scientists were able to identify the influence caused by factors unique to the blood of young mice, which could ultimately be used as treatments for age - related neurodegenerative disorders.

In a mice experiment, the amount of brown fat cells in older mice was maintained at almost the level equivalent to that of younger mice.