Sentences with phrase «other solid tumors»

The authors hope that this work may provide the basis for the start of a clinical trial for ovarian cancer, and indeed, for other solid tumors.

«But mounting evidence confirming angiotropism and EVMM has revolutionized the knowledge of how cancer spreads through the body to the point that other scientists have confirmed the process in other solid tumor cell types such as pancreatic cancer.»

In most other solid tumors with a SWI / SNF loss, a compensatory upregulation of other members of this protein complex counteracts the functional loss of any single component.

Based on the results, St. Jude plans to expand biopsies to include recurrent rhabdomyosarcoma tumors and possibly other solid tumors.

Other malignancy (including MDS and MGUS) within the last 5 years except: adequately treated non-melanoma skin cancer or other solid tumors curatively treated with no evidence of disease for ≥ 5 years.

Preclinical research has encouraged us to explore the potential therapeutic benefit of Toca 511 & Toca FC in multiple other solid tumor cancers.

«The work will have direct implications for designing clinical trials using oncolytic viruses, not only for brain tumors, but for other solid tumors.»

Unlike other solid tumors, RCC is unique in that debulking nephrectomy has been the mainstay of therapy even in the setting of metastatic disease.

Building on the advancements made in other solid tumors, as well as a better understanding of cancer immunology, provides hope for the development of novel and effective immunotherapies in the treatment of sarcoma.

We do know the consequences of untreated celiac disease — an increased risk for lymphomas and other solid tumors, along with a host of associated auto - immune, neurological and endocrine diseases.

At Seattle Children's, pediatrician and bioethicist Douglas Diekema was drafted by colleagues to offer ethical guidance on what to do if the hospital can't make enough CAR - T cells for everyone in planned trials in brain and other solid tumors, as well as more leukemia trials.

«Our preclinical study indicates that SapC - DOPS does both and inhibits the growth of new tumor blood vessels, suggesting that this agent could one day be an important treatment for glioblastoma and other solid tumors.»

SapC - DOPS (saposin - C dioleoylphosphatidylserine), is a nanovesicle drug that has shown activity in glioblastoma, pancreatic cancer and other solid tumors in preclinical studies.

«Prostate cancer cells, as well as some other solid tumors, have been shown to contain higher cholesterol levels than normal cells,» said senior author Donald McDonnell, Ph.D., chairman of the Department of Pharmacology and Cancer Biology at Duke.

To understand why this occurs, they examined the effect of a CDK4 / 6 inhibitor called abemaciclib in mice with breast or other solid tumors.

The companies have launched a phase II trial of the antibody - drug conjugate, and are also testing it in other solid tumors, including ovarian and non — small - cell lung cancers.

The role of genetic alterations in the microenvironment of sporadic and heritable breast carcinomas and other solid tumors are being examined as they relate to clinical outcome.

Her primary research interest has been in neuroblastoma and other solid tumors in children.

If clinical trials of anti-PD-1 continue to show promising results, cancer patients may soon have access to another powerful immunotherapy for the treatment of numerous cancers, including melanoma, non-small cell lung cancer, and other solid tumors.

NY - ESO - 1 is one of the few tumor antigens that have restricted expression in normal tissue but become aberrantly expressed in epithelial ovarian cancers and other solid tumors.