Sentences with phrase «pure population»

Once they had pure populations of cells, they compared their patterns of gene expression, as well as changes in the structure of the DNA.

In future studies, the researchers plan to further improve the protocol to generate pure populations of various hormone - releasing cell types, enabling the production of grafts that are tailored to the needs of individual patients.

There is a plan, however, to maintain a genetically pure population of Cuban crocodiles by breeding the species and then releasing them into the wild.

Obtaining pure populations of endothelial cells has been difficult because many of the markers used to distinguish endothelial cells are also expressed by a variety of other vascular cells (8).

This approach not only enables us to get highly pure populations of DA progenitor cells (> 90 %), but it also increases our final yield of transplantable cells > 40 times when compared to previous embryoid body protocols starting with the same number of cells.

Deng and his colleagues next induced the stem cells to develop into separate pure populations of astroglial cells and neurons.

Notably for their analysis, the researchers employed a powerful cell sorting technique to allow them to study pure populations of heart muscle cells (cardiomyocytes) rather than a mix of all cell types in the heart — which, due to an alteration in composition during disease, would confound analysis.

Postdoctoral fellow Zhexing Wen, Ph.D., coaxed the skin cells to form five lines of stem cells and to mature into very pure populations of synapse - forming neurons.

The ability to make pure populations of these cells within days rather than the weeks or months previously required is a key step toward clinically useful regenerative medicine — potentially allowing researchers to generate new beating heart cells to repair damage after a heart attack or to create cartilage or bone to reinvigorate creaky joints or heal from trauma.

Researchers at the Stanford University School of Medicine have mapped out the sets of biological and chemical signals necessary to quickly and efficiently direct human embryonic stem cells to become pure populations of any of 12 cell types, including bone, heart muscle and cartilage.

To generate almost pure populations of human podocytes in cell culture, Samira Musah, the study's first author and HMS Dean's Postdoctoral Fellow who is working with Ingber at the Wyss Institute, leveraged pieces of the stem cell biologists» arsenal, and merged them with snippets taken from Ingber's past research on how cells in the body respond to adhesive factors and physical forces in their tissue environments.

Genetically pure populations of westslope cutthroat trout are known to occupy less than 10 percent of their historical range.

Sorting breast cancer cells using a new reporter construct allows the interrogation of a highly pure population of cancer stem cells and may allow for the discovery of new therapeutic targets

Functional and phenotypic differences of pure populations of stem cell - derived astrocytes and neuronal precursor cells.

The findings, published Aug. 31 in the journal Science Advances, could also lead to a simple, scalable and inexpensive way to manufacture a pure population of bone - building cells.

Although some teams have managed to produce nearly pure colonies of certain kinds of neural cells from ES cells, no one has managed to concoct a recipe that will direct the cells to become, say, a pure population of dopamine - producing neurons that could replace those missing in Parkinson's disease.

According to the authors, future studies should aim to improve the efficiency of the approach to generate a pure population of cells that closely mimic adult Leydig cells.

«Those approaches take a long time, it is difficult to isolate a pure population, and the NPC - like cells are still transient,» says Zhongwei Li, a research associate in the Izpisua Belmonte lab and co-first author of the new paper.

After this period of induction, keratinocytes derived from pluripotent stem cells were isolated and amplified to obtain a homogenous and pure population of keratinocytes presenting all the phenotypic characteristic of adult keratinocytes.

The goal is to help researchers establish a pure population of subjects who truly have the disease, ultimately enabling the discovery of pathogenic pathways.

However, with few exceptions, the stem cell and regenerative medicine industry has remained inadequately capitalized to carry out large - scale clinical trials independently, and major pharmaceutical firms have tended to show more interest in the use of hiPSCs as a source of large, pure populations of specific somatic cells for use in drug compound screening and toxicology tests, than they have in therapeutic uses of stem cells and their derivatives.

I can see D.C. and New York (because NYC overshadows the rest of the state with a pure population advantage) because of government and finance.

Because the antigen detected is produced only by the female worm, a pure population of male heartworms will give a false negative, also.

Because the antigen detected is produced only by the female worm, a pure population of male heartworms will also give a false negative.

There is prolific wildlife throughout the Island: visitors can expect to see some of the 325 species of birds including Australia's stork, the jabiru, several species of wallaby, possums, flying foxes, echidnas and eastern Australia's purest population of dingo.

The wildlife that visitors to Fraser Island can expect to see is some of the hundreds of species of birds including Australia's stork, the jabiru, possums, flying foxes, echidnas and eastern Australia's purest population of dingo.