Sentences with phrase «quiescent state»
The phrase "quiescent state" refers to a condition of calmness, rest, or tranquility. It implies a state of inactivity or quietness, where there is no disturbance or movement. Full definition
Multiwavelength Study of Quiescent States of Mrk 421 with Unprecedented Hard X-Ray Coverage Provided by NuSTAR in 2013
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The implants were tested in an animal model and the team observed a significant reduction in T cell activation, meaning that the vaginal tract was demonstrating an immune quiescent state.
MSCs are considered adult or somatic stem cells and remain in a non-proliferative, quiescent state during most of their lifetime, until stimulated by the signals triggered by tissue renewal, damage and remodeling processes.
I will discuss our latest results showing that satellite cells in their homeostatic quiescent state are equipped with quality control mechanisms to preserve their fitness, and how age - associate alterations in these protective mechanisms lead to stem cell loss of function and regenerative capacity.
The last such quiescent state occurred in the late seventeenth century.
This primes the cells to fuse, causing some to quickly become muscle fibers and others to stick to those fibers and remain stem cells in their quiescent states.
The key is to create a niche, 3 - D microenvironment that encourages some cells to become muscle fibers and others to go into what he calls a «quiescent state.»
«Our organotypic models demonstrate the power of the microenvironment by showing that normal cells in their native architecture naturally steer fully malignant, genotypically aberrant tumor cells into a quiescent state,» Ghajar says.
If no cell production is required, the stem cells remain in a quiescent state,» explained Dr. Christian Berger of the Institute of Genetics at Mainz University.
One possible answer for the biological meaning of the quiescent state of male germ cells may be to prevent the gonad from being feminized until masculinization of somatic cells is established.»
«Our analyses using medaka collectively also suggest that germ cells acquire the feminizing effect before committing to gametogenesis, while male germ cells undergo a quiescent state before the initiation of spermatogenesis,» corresponding author Minoru Tanaka says.
Many of these progenitors are maintained in a quiescent state or «standby mode» and are ready to differentiate in response to immune challenges (such as stress, infection or disease).
«Satellite cells can sit around for practically a lifetime in a quiescent state, not doing much of anything.
Such insight will uncover the manner by which these cells exit from the quiescent state and become activated and drawn towards sites of inflammation and injury in order to trigger and enhance tissue regeneration.
We also show that a general repression of translation, mediated by the phosphorylation of translation initiation factor eIF2 at serine 51 (P - eIF2α), is required to maintain the quiescent state.
His lab has developed a screen to identify small molecules that revert PSCs to their quiescent phenotype using the accumulation of lipid droplets as a hallmark of the quiescent state.
Low oxygen levels in the HSC «niche» keep stem cells in a quiescent state, protecting them against oxidative stress and maintaining their integrity until they are needed to make new cells, researchers surmise.
The SCs are normally kept in a quiescent state and activated upon exposure to stimuli, such as exercise or SkM injury.
With the ability to mount a response against virtually any foreign material and return to a quiescent state following neutralization of the threat, this fascinating organ system displays remarkable specificity and plasticity.
Even more concerning, flea cocoons allow adults to enter a quiescent state for up to 6 months, where they will delay emerging until they detect a potential host.
Within their cocoon, adult fleas can enter a quiescent state that lasts for up to 5 months.
Inside its cocoon, an adult flea can remain in a quiescent state until a suitable host is detected nearby.
Metabolic activity is low in the quiescent state, which allows for the prolonged survival.
Adult fleas can enter into a quiescent state for up to 5 months.