"Renal cells" refer to the cells that are found in the kidneys, which are the organs responsible for filtering waste and excess water from the blood to produce urine.
Full definition
The results are explained in «Antioxidant micronutrients and the risk
of renal cell carcinoma in the Women's Health Initiative cohort,» featured in the Feb. 15 issue of Cancer.
A Phase III, Multicenter, Randomized, Placebo - Controlled, Double - Blind Study Of Atezolizumab (Anti − PD - L1 Antibody) As Adjuvant Therapy In Patients
With Renal Cell Carcinoma At High Risk Of Developing Metastasis Following Nephrectomy
Based on this finding, the researchers found that similar mutations also occur
in renal cell carcinomas in humans.
A Phase II Study of the Efficacy and Safety of Axitinib Given on an Individualized Schedule for Metastatic
Renal Cell Cancer after Treatment with PD - 1 or PD - L1 Inhibitors
High - dose interleukin - 2 for the treatment of
metastatic renal cell carcinoma: a retrospective analysis of response and survival in patients treated in the surgery branch at the National Cancer Institute between 1986 and 2006.
Adults with
advanced renal cell carcinoma after targeted therapy against vascular endothelial growth factor (VEGF)
Researchers led by Van Allen and Choueiri sought an explanation for why some patients with a form of metastatic kidney cancer called clear
cell renal cell cancer (ccRCC) gain clinical benefit — sometimes durable — from treatment with immune checkpoint inhibitors that block the PD - 1 checkpoint, while other patients don't.
A month's treatment
for Renal Cell Carcinoma using Pfizer's Sunitinib would cost about Rs 1.75 lakh.
Differential expression of KAI1 metastasis suppressor protein in
renal cell tumor histological subtypes.
«
Most renal cell carcinomas learn to escape therapy after a couple of years,» said Robert Weiss, professor of medicine at UC Davis, chief of nephrology at Sacramento VA Medical Center, and head of the kidney cancer working group at the UC Davis Comprehensive Cancer Center.
An FDA approved drug to
treat renal cell carcinoma appears to reduce levels of a toxic brain protein linked to dementia in Alzheimer's and Parkinson's diseases when given to animals.
They discovered that overactivation of this pathway, which is observed in some types of cancer such
as renal cell carcinoma, melanoma and pancreatic cancer, is important to promote and support the growth of cancer cells in culture and animal models.
Stein MN, Hirshfield KM, Zhong H, Singer EA, Ali SM, Ganesan S. Response to crizotinib in a patient with MET - mutant
papillary renal cell cancer after progression on tivantinib.
Kidney cancer — also
called renal cell cancer — is one of the major types of cancer for which new immune - based cancer treatments are currently in development.
Contrasting properties of hypoxia - inducible factor 1 (HIF - 1) and HIF - 2 in von Hippel - Lindau -
associated renal cell carcinoma
«
Because renal cell carcinoma most often presents as incidental, small, localized, and often indolent tumors in elderly patients with high rates of CKD and comorbidities, competing nononcologic mortality risks should be carefully considered when counseling patients.»
They constructed both modules from biological components, such as various genes and proteins, and incorporated them into
cultivated renal cells.
In this webinar, we will hear from experts about different ways to isolate and characterize specific cell populations, including the nephrogenic progenitors that give rise to mature
functional renal cells and mesenchymal stem cells which can differentiate into multiple cell types.
Researchers at UC Davis have shown that docosahexaenoic acid (DHA), a fatty acid commonly found in fish and fish oil supplements,
reduces renal cell carcinoma invasiveness, growth rate, and blood vessel growth when combined with the anti-cancer therapy regorafenib.
Tang and his colleagues in the laboratory of Dr. David Hsu at the Duke Cancer Institute
implanted renal cell carcinoma tumors into mice and then treated the animals with sulfasalazine, a drug that blocks cystine uptake.
Diets high in meat may lead to an increased risk of
developing renal cell carcinoma (RCC) through intake of carcinogenic compounds created by certain cooking techniques, such as barbecuing and pan-frying.
PHIII Randomized Study Comparing Perioperative Nivolumab vs. Observation in Patients with
Localized Renal Cell Carcinoma Undergoing Nephrectomy.
In an effort to further exploit the potential of Pexa - Vec to activate the immune system to fight cancer, as seen in McDonald's preclinical data, SillaJen recently announced a new clinical trial in collaboration with New York - based Regeneron Inc. to test Pexa - Vec and REGN2810, a PD - 1 checkpoint inhibitor, in combination
against renal cell carcinoma, and recently signed a sponsored research agreement with UCSF to enable joint support of parallel preclinical experiments by McDonald's team.
First - line combination therapy with the programmed death ligand 1 (PD - L1) inhibitor avelumab and the vascular endothelial growth factor receptor tyrosine kinase inhibitor axitinib resulted in encouraging antitumor activity in patients with previously
untreated renal cell carcinoma (RCC) and had a manageable toxicity profile, according to the results of the JAVELIN Renal 100 study published in Lancet Oncology.
Additionally, purple corn can potentially reduce the risk of heart disease-most likely due to decreased coagulation of platelets and increased circulation of HDL cholesterol, and can prevent long term kidney damage in people with type 2 diabetes by
protecting renal cells.
Renin -
producing renal cell carcinomas — clinical and experimental investigations on a special form of renal hypertension
About Blog The KCCure blog covers kidney cancer research news and stories
about renal cell carcinoma clinical trials and treatments to cure kidney cancer.
Early this week, the U.S. Food and Drug Administration (FDA) approved a combination immunotherapy regimen for treating certain patients newly diagnosed with
advanced renal cell carcinoma, the most common form...
Project Title: Identification of molecular alterations associated with the progression of clear
cell renal cell carcinoma by mass spectrometric approaches
Javidnia says analysis in this study shows pazopanib penetrates the mice's blood - brain barrier when given the equivalent of half of dose given
for renal cell carcinoma treatment.
They then mutated three of these genes simultaneously
in renal cells of mice, which then developed renal cancer.
Freed SZ, Halperin JP, Gordon M. Idiopathic regression of metastases
from renal cell carcinoma.
Axitinib, a drug used to
treat renal cell carcinoma, has been shown to be effective at inhibiting the Abl kinase activity in patients with BCR - ABL1 (T315I).
The researchers began by identifying the genes that often mutate in
human renal cell carcinomas.
The changes, present in about 10 percent of
renal cell tumors (the most common type of kidney cancer), boosted mTOR activity, which meant they aided tumor growth with or without ADZ8055.
Meanwhile, a recent U.S. study found an increase in the risk of
renal cell cancer among those taking the painkillers regularly for four to ten years.
They found those who consumed the most vegetables and fruits had a lowered risk
of renal cell cancer by 32 percent compared with those who consumed the smallest amounts of these antioxidant - rich foods.
Researchers studied food questionnaires for 335 people with
renal cell carcinoma, the most common form of kidney cancer, and 337 healthy controls.
Mr. Kaisary's main interest is the diagnosis and management of prostate cancer and benign prostate disease together with bladder cancer and
renal cell carcinoma.
Renal cell carcinoma, also known by the eponym Grawitz tumor, is the most common form of kidney cancer arising from the renal tubule.