Sentences with phrase «response to chemotherapy»

The imaging system may be able to predict response to chemotherapy as early as two weeks after beginning treatment.

In addition, he applies 3 - D techniques to aid in the detection and staging of pancreatic cancer, and in the evaluation of tumor response to chemotherapy.

This analysis found that combination therapy helped to eliminate minimal residual disease (MRD) in young AML patients who initially had a poor response to chemotherapy.

Cancer cells had essentially figured out how to survive by rewiring their metabolism in response to chemotherapy.

«Predicting response to chemotherapy for triple - negative breast cancer patients: New method.»

Researchers at Yale Cancer Center have identified a new subtype of triple negative breast cancer that shows significantly improved response to chemotherapy.

Their machine learning technology coupled with digital holography produced an 84 percent success rate in predicting canine responses to chemotherapy.

All had levels of residual disease that indicated a poor initial response to chemotherapy alone, including nine with MRD levels of 25 percent or more.

«Gene - regulatory factors shown to improve pancreatic cancer response to chemotherapy.»

The researchers are now conducting an individual patient analysis to correlate response to chemotherapy with the fall in VEGFR receptor levels in the blood.

«Paclitaxel is one of the preferred chemotherapies for use in breast cancer, and our findings indicate that anti-TIM-3 antibodies currently in clinical development should also be considered in this setting as a means to improve upon the immune - dependent response to chemotherapy,» explained Brian Ruffell, Ph.D., assistant member of Moffitt's Department of Immunology.

As research indicates that the level of SFRP2 expressed by the tumors increases as the tumor develops, the team will also investigate whether the technique can be used to track tumor growth, making it useful for monitoring response to chemotherapy.

In the metastatic setting, complete responses to chemotherapy for sarcoma are rare and the median survival is 10 - 15 months.

This Team is studying vitamin D receptors to determine if it is an effective «super-enhancer» which improves patient response to chemotherapy.

Epigallocatechin -3-gallate (EGCG) found in green tea even acts as an antiangiogenic and antitumor agent, and helps modulate tumor cell response to chemotherapy.30

In cats without feline leukemia, mediastinal lymphoma often shows at least a partial response to chemotherapy.

Specific projects include the use of gene expression signatures to predict recurrent rectal cancer, the study of gene expression changes in response to chemotherapy and radiation, differential gene expression between primary tumor and metastatic deposits, and analysis of expression patterns to provide more accurate cancer staging.

Patients were categorized into those who had a good response and those who had a poor response to chemotherapy, based on a recently approved chemotherapy response score that correlates with progression - free and overall survival.

To more directly assess the role of GSTO1 and RYR1 in the breast tumor response to chemotherapy, the researchers injected human breast cancer cells into the mammary gland of mice and then treated the mice with carboplatin after tumors had formed.

In Zitvogel's lab, Delahaye studied how understanding the role of the immune system in cancer could help doctors predict clinical outcomes and response to chemotherapy.

The results were more pronounced in those who had a good response to chemotherapy, compared with those who had a poor response to chemotherapy.

Findings based on this new technology are likely to have a profound impact on improving the detection and diagnosis of diseased cells and in evaluating a patient's response to chemotherapy.

In 2006 Potti's team published several papers in high - profile journals reporting that certain gene expression signatures predicted a patient's response to chemotherapy.

Potti is a co-investigator on research at Duke led by Joseph Nevins on using gene - expression arrays to predict a cancer patient's response to chemotherapy.

Today, The New York Times reports that on Sunday Duke decided to halt enrollment in three clinical trials in which Potti and Duke's Joseph Nevins were using gene - expression signatures to predict a patient's response to chemotherapy.

During the stress response that occurs as a cell becomes cancerous, and in response to chemotherapy, p53 attempts to repair DNA damage that has occurred, and, if not successful, p53 orders the cell to die.

That the quality of the tumor's blood vessels could dictate the patient's response to chemotherapy could be one reason that two patients with similar cancers respond differently to the same therapy.

Autocrine Prolactin Stimulates Endometrial Carcinoma Growth and Metastasis and Reduces Sensitivity to Chemotherapy Endocrinology February 15, 2017 Keshuo Ding, Yan Yuan, Qing - Yun Chong, Yulu Yang, Rui Li, Xiaoni Li, Xiangjun Kong, Pengxu Qian, Zirui Xiong, Vijay Pandey, Lan Ma, Zhengsheng Wu, Peter E. Lobie, and Tao Zhu Advanced and recurrent endometrial carcinoma (EC) exhibits a poor response to chemotherapy and low survival rates.

But these epigenetic drugs have shown some success in improving patients» response to chemotherapy or immunotherapy, or in overcoming resistance to those standard treatments.

A biopsy of each patient's cancer will be screened for 600 genes as well as protein expression to uncover molecules and pathways that are driving the cancer and to predict a patient's response to chemotherapy or other tailored therapy.

An award of $ 82,500 over roughly nine months bolstered Kuang's research, which aims to determine which combination of molecular imaging and biomarkers can provide early insight into a patient's response to chemotherapy.

«We want to test the direct role of these transcription factors in the development of aggressive disease and response to chemotherapy.

Malignant: none effective, may need to consider euthanasia; systemic: poor response to chemotherapy; cutaneous: corticosteroids, relapse is common, especially in Shar - Peis

Staging used to be done regularly after the initial diagnosis of lymphoma but it has since been found that stage of disease does not impact upon the response to chemotherapy (i.e. it is not true that a stage II will have a better response than a stage IV) and thus there isn't much point to going through the trouble and expense of staging.

Patients with stage V lymphoma tend to have a poor response to chemotherapy and it may be helpful to stage the patient to rule out whether or not the patient is in Stage V.

If a biopsy has not been performed, it may be a good idea to have one done so as to gain the maximum information about the tumor (whether it is slow or fast growing, what type of lymphocytes are involved etc.) as this information can help predict the response to chemotherapy.

Responses to chemotherapy are minimal in cases of MCT.