In drug design, for example, the function of a protein is determined
by sequence comparison and 3D modelling programs.
Other theories hold that the prokaryotes that gave rise to early eukaryotes were probably from the Domain Archaea, both because of several key characteristics and because
DNA sequence comparison suggest that archaeans are more closely related to the eukaryotes than are eubacteria.
Uppsala researchers Patric Jern, Alexander Hayward, Göran Sperber, and Jonas Blomberg used the computer program RetroTector and detailed
sequence comparisons in so - called phylogenetic studies to map the retrovirus part of the pig genome.
The goal is to identify the genes necessary to install C4 photosynthesis in rice through different approaches, including genomic and
transcriptional sequence comparisons and mutant screening.
Sequence comparisons placed the telomerase proteins in the reverse transcriptase family but revealed hallmarks that distinguish them from retroviral and retrotransposon relatives.
Now sequence comparisons with rats, mice and dogs show that the X chromosome seems to have changed little since the evolution of placental mammals, supporting the idea that once genes are transferred to X, they stay there.
Oehmen is the originator of ScalaBLAST, a massively parallel implementation of the Basic Local Alignment Search Tool (BLAST) used in
biological sequence comparison applications, which outperforms in speed and capacity any other parallel implementation.
Due to the massive availability of sequences of genomes of microbes and other organisms, comparative genomics has gained recognition as a powerful tool for deciphering biological processes both
through sequence comparisons and comparative regulation.
For example, large - scale taxonomic
DNA sequence comparisons have established more rigorous relationship trees and taxonomic distances for the large and diverse class Aves (birds) and the phylum Arthropoda.
Microbial Forensic Analysis of Bacterial Fingerprint by
Sequence Comparison of 16S rRNA Gene — So - Yeon Lee — Journal of Forensic Research — June 2015
In the last two decades, DNA
sequence comparison has gradually been added as a tool in the kit for species delimitation, casting light on a number of cryptic species where neither morphological nor bioacoustic differences provided clues for species differentiation.
Most orthology determination methods make use of
sequence comparisons: the amino acid sequences of all proteins in two species are compared with each other, and the two sequences that are most similar are considered to be orthologs.
To this purpose, GenProfile utilizes a powerful technology platform, which involves proprietary high - throughput technologies for gene
sequence comparison (e.g., multiplex sequence comparison), genotyping (MALDI - TOF minisequencing), unique approaches to data analysis and interpretation, as well as a large network of clinical collaborators.
Sequence comparisons of proteins thousands of different prokaryotes, together with assumptions of the slow mutation rate of prokaryotes lead to estimates that major classes of primitive microbes (chemotrophs and photosynthetic autotrophs) fused together more than 2.5 billion years ago in a process called endosymbiosis.
Sequence comparison (BioEdit) of selected published variants of the original eqFP578 to that of the five Amrose variants (v0 - v4).
Sequence comparison of the polymerase gene of paramyxoviruses has revealed six highly conserved domains (I to VI), which are predicted to be essential for the key functions of RNA binding, RNA replication, and protein kinase activity [17], [18].