Indeed selected compounds demonstrated efficacy
in several animal models of CNS related disorders such as depression, obesity, addiction, and psychosis.
Thankfully, since we've already seen gene - silencing drugs work in
several animal models of HD, it's clear that this new research doesn't invalidate that approach.
Researchers from University College London, the University of Kent and the University of Groningen started examining the enzyme's involvement in aging after the immune - suppressing drug rapamycin, known to inhibit Pol III, was seen to extend the lifespan of
several animal models including mice.
Dr. Tarazi and his group have also
established several animal models that provide close presentations of the core symptoms of neuropsychiatric conditions, and have efficiently utilized these models for assessing the actions of standard and experimental medications.
In the paper, the authors
use several animal models to show that the progenitor cells could contribute to the formation of new lymph ducts, both by becoming part of the lymph ducts and by stimulating the growth of nearby cells.
Selective 5 - hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: Identification of drugs
in several animal models of CNS related disorders.
The research team, led by Thomas M. Kristie, PhD, Chief of the Molecular Genetics Section in the National Institute of Allergy and Infectious Diseases» Laboratory of Viral Diseases, and also included Timothy Foster, PhD, LSU Health New Orleans Associate Professor of Microbiology, Immunology & Parasitology, studied herpes simplex virus (HSV) infection in
several animal models.
In 1995, University of Chicago researchers demonstrated that gene therapy, using a virus, could be used to combat restenosis following angioplasty in
several animal models.
Keto diets have been shown in
several animal models to decrease pain.