A
synthesis pathway refers to the step-by-step process of creating or forming something by combining different elements or building blocks together.
Full definition
While glyphosate is not toxic to mammalian cells it «works» on plants by disrupting the Shikimate pathway which happens to also be a critical amino acid
synthesis pathway for bacteria.
They used the AHL quorum - sensing molecule to shut off an enzyme that moves shikimate further along in the amino
acid synthesis pathway, allowing shikimate to build up in the cells.
«This latest finding provides a concise and
direct synthesis pathway that, due to the structure of the products delivered, will likely be quite valuable for the discovery and development of therapeutic agents,» says Micalizio, whose work focuses on the design of organic chemical reaction methods and strategies to improve medicine and human health.
The newly discovered
fumisoquin synthesis pathway shows that there was a parallel development for the production of isoquinoline alkaloid compounds in both groups of organisms.
Using genes from these chromosomal regions, Richter identified three new enzymes that function in
terpene synthesis pathways to produce linalool, nerolidol, and other terpenes.
Cellular Studies (CEL): The study of animal cells involving the use of microscopy to study cell structure and studies investigating activity within cells such as enzyme pathways, cellular biochemistry, and
synthesis pathways for DNA, RNA, and protein.
Patients with GNEM have mutations in a gene controlling a key enzyme in
the synthesis pathway for sialic acid (SA).
Also, because it is involved in such a critical step in
the synthesis pathway, the regulation of the DSYB gene by environmental conditions is of great significance in determining how much DMSP is ultimately produced.»
Through the exploration of materials, Los Alamos pursues the discovery science and engineering required to establish design principles,
synthesis pathways, and manufacturing processes for advanced and new materials to intentionally control functionality relevant to the Lab's national security mission.