Sentences with phrase «therapeutic avenues»
Future studies aimed at whether this is a productive versus a faulty adaptive fuel shift could lead to new therapeutic avenues for heart failure.
sciencedaily.com
This new information might also provide a new therapeutic avenue researchers could explore as a means to reduce risk of liver injury in some people.
This research, published online in Nature Structural & Molecular Biology on Aug. 17, 2014, reveals exciting new insight into potential therapeutic avenues for cancer treatment.
Epigenetic dysregulation has been implicated in neurodegenerative disorders, while targeting histone acetylation is a promising therapeutic avenue for PD.
The ecRNAs, they say, are fundamental regulators of DNA methylation patterns in the adult brain through interaction with DNA methyltransferase enzymes, and the ecRNAs may offer a promising future therapeutic avenue to treat neuropsychiatric disease states associated with changes in DNA methylation, as they report in the July 7 issue of Nature Communications.
Moreover, it can enable pre-clinical and clinical trials linking cellular and systems levels for successful therapeutic avenues.
Therefore, developing drugs that block the ability of cancer cells to disseminate is a major anti-cancer therapeutic avenue.
«Disruption of the exosomal metabolic adaptation of cancer cells could provide a novel therapeutic avenue for exploitation,» he said.
He will present and demonstrate the foundations of treatment while detailing the elements of SPACE, which offers clinicians a number of proven, integrated therapeutic avenues and techniques.
In all, 22 noted scientists and clinicians spoke on CDG research and future potential therapeutic avenues.
In contrast, re-introduction of neurogenesis or stimulation of neuroplasticity in the adult brain both represent promising therapeutic avenues to improve psychiatric and neurodegenerative conditions.
A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) identifies potential new therapeutic avenues for patients with Alagille syndrome.
«There's a lot of work needed before we want to seriously propose that this is going to be a therapeutic avenue,» says Rowitch.
This study provides a therapeutic avenue to explore.»
But the discovery of A20's crucial regulatory role should open up new therapeutic avenues.
«Although this mutation only exists in a small percentage of cases, this discovery points to a potential therapeutic avenue for these patients.»
«Understanding how wounds can be healed is believed to be very important and a potential therapeutic avenue for the treatment of inflammatory bowel disease,» said Dr. Tim Denning, associate professor in the Institute for Biomedical Sciences at Georgia State.
«Understanding the mechanisms that promote aberrant neurogenesis caused by traumatic brain injury and subsequent seizures may open new therapeutic avenues to prevent epilepsy and associated memory problems caused by impact,» said senior author Dr. Jenny Hsieh, Associate Professor of Molecular Biology and a member of the UT Southwestern Hamon Center for Regenerative Science and Medicine.
Two drugs recently showed promise in clinical trials, and now a study in Science Translational Medicine offers both an unprecedentedly deep explanation of how the disease progresses and introduces another potential therapeutic avenue.
The findings provide insight into the biological pathways that may predispose an individual to disease and could ultimately lead to the development of new therapeutic avenues to treat the five major psychiatric illnesses.
Increasing the oxygen delivery to these muscles through beetroot can provide a therapeutic avenue to improve the quality of life for these patients.»
«This is a new therapeutic avenue,» said Yi Lai, PhD, the leading author of the study and assistant research professor in the MU School of Medicine's Department of Molecular Microbiology and Immunology.
The finding also opens up new therapeutic avenues that can modulate and fine tune the processes to treat associated medical conditions.
«The findings open new therapeutic avenues, particularly for the Group 3 and 4 subtypes where patient outcomes are inferior for the majority of affected children.»
The results may open up new therapeutic avenues for the treatment of malignant melanoma, demonstrate a new type of immune recognition and could even shed new light onto the incipient events causing the development of vitiligo.
«Any compound that targets these factors opens up a new therapeutic avenue for cancer,» Pelletier notes.
As a consequence, modulating nucleocytoplasmic transport could become a promising and new therapeutic avenue.»
Develop and de-risk new therapeutic avenues to treat serious, complex human disease by understanding the biological mechanisms.
«The findings open new therapeutic avenues, particularly for the Group 3 and 4 subtypes, where patient outcomes are inferior for the majority of affected children,» said Paul Northcott, PhD, of St. Jude Developmental Neurobiology.
These unique experimental models have been yielded mechanistic insight and potential new therapeutic avenues.
This overview describes how newly identified genes implicated in human neurodegenerative diseases are making their way into the easy - to - manipulate fruit fly and providing new insights into disease pathology and therapeutic avenues.
Therefore, identifying bioactive molecules able to target the enteric nervous system, which controls the motility of intestinal smooth muscle cells, represents a new therapeutic avenue.