Sentences with phrase «to affect neurons»

It's too soon to ask if this is how it happens in a patient; instead we are asking how do these drugs affect neurons.

A separate analysis showed a similar drop in netrin - 1 in affected neurons in rats whose axons from the brain to the spinal cord had been cut.

However, blocking TSP1, 2 and 4 did not affect neuron survival, suggesting that there is some other factor in the UTC cells that promotes cell longevity.

The researchers plan to investigate what percentage of individuals individuals with intellectual disability and autism may carry CC2D1A mutations and to determine whether other genes affect neurons in a similar fashion.

Another hypothesis is that instead of secreting chemicals, astrocytes exert their effects by controlling the uptake of neurotransmitters from the space surrounding neurons, thereby affecting neuron activity indirectly.

S100B released by astroglial cells promotes harmful astroglial activation (astrogliosis) and adversely affects neurons, causing them to die at increased rates or develop in multiple dysfunctional ways.

Zheng wondered how rapamycin would affect the neurons plagued by the diseased mitochondria.

Something present in the fluid surrounding the neurons in the bath with the hUTCs was apparently affecting the neurons.

Further study is needed to analyze whether a compact scar tissue indeed improves recovery and how this process affects the neurons» ability to reform connections with each other.

That should help scientists better see how a disease affects neurons throughout the body — like how a stroke can cause neuromuscular weakness — because it's nearly impossible to reconnect the millions of neurons throughout a rodent body once dissected.

The α - syn clumps, called Lewy bodies, eventually kill affected neurons, which leads to clinical PD.

«Stem cells reveal how illness - linked genetic variation affects neurons.»

Diffusion tensor images like this one (rendered differently than the previous image) can reveal how a brain tumor has affected neuron connections or can help guide brain surgery.

One is how RCAN1 affects neurons in a portion of the brain called the basal forebrain, which also responds to NGF.

But researchers at Wake Forest University Baptist Medical Center in Winston?Salem, N.C., found that ALS - affected neurons undergo a process known as «denervation» that severs the connection.

At a later stage, mimicking the second trimester, Zika still preferentially infected neural progenitor cells, but it also affected some neurons.

Parkinson's primarily affects neurons in the an area of the brain called the substantia nigra.

Thanks to an $ 11 million grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS), Gan will lead a collaboration among national scientists to study how the protein tau affects neurons in the brain and how it causes disease, particularly frontotemporal dementia.

Neurodegenerative diseases are genetic or periodic conditions affecting the neurons of the human brain.

«More importantly, a retrovirus can infect only dividing cells such as reactive glial cells, but it does not affect neurons, which makes it ideal for therapeutic use with minimal side effect on normal brain functions.»

Parkinson's disease (PD) affects neurons in a region of the brain called the substantia nigra.

Corn, and plenty of other crops, use pesticides with chemicals known as neonicotinoids (they affect neurons, and are similar to nicotine).

Due to the simultaneous strengthening of all of the synapses of the affected neurons, major reductions in the neuronal activity can be normalised again with surprising speed.

For the new study, Dokholyan's team, including lead author Cheng Zhu, PhD, a postdoctoral researcher in his lab, conducted complicated experiments to compare how trimers affect neurons to how larger fibrils affect neurons.

After just a few hours, they could clearly observe how the contact points between the affected neurons and their neighbouring cells increased in size.

Although it might seem crazy that gut bacteria could affect neurons, evidence for that has been steadily accumulating, so much so that an international consortium is devoted to understanding which microbes protect against or promote MS.

While Aβ is made in all human brains as they age, differences in the rate at which it is produced and eliminated from the brain and in how it affects neurons, means that not everyone develops dementia.

It affects neurons in the brain that produce dopamine.

Blue 1: According to CSPI: «One (unpublished) animal test suggested a small cancer risk, and a test - tube study indicated the dye might affect neurons.

Oligodendrocyte death, occurring after a spinal cord injury, activates a process called de-myelination that results first in damage to surviving neuronal connections and finally in death of the affected neurons.

Fred H. Gage of the Salk Institute for Biological Studies and his colleagues attempted a new strategy to deliver the protein to affected neurons.

In nearly half of all FTD cases and in 97 % of the ALS cases, there is an accumulation of the protein TDP - 43 in the affected neurons, the basic working units of the nervous system.

«MRI scans give us a bird's eye view of the apnea - related difference in volume of various parts of the brain, but they don't tell us, at the cellular level, what happened to the affected neurons or when,» said co-author David Gozal, MD, professor of pediatrics, University of Chicago.

Precise knowledge of which stretches of the genome are pillars for stem cells, or metastasized tumor cells, or alzheimers - affected neurons, or [your cell line of interest], is the foundation of precision medicine.

Did the higher acidity and lower levels of TrkB signaling affect the neurons?

Scientists at the Whitehead Institute used CRISPR / Cas9 gene editing method to restore activity to the fragile X syndrome gene in affected neurons.

Using CRISPR genome editing in human neurons, Krogan's team will delete all 600 genes, one by one as well as in combination, to determine how each one affects the neurons» health.

Many of the affected neurons signal via the neurotransmitter dopamine; thus traditional therapy continues to rely on dopamine replacement therapy.

ALS (amyotrophic lateral sclerosis), also known as Lou Gehrig's Disease, is a progressive neurodegenerative disease that affects neurons (nerve cells) in the brain and the spinal cord.

Instead, a very small number of neurons specifically activated by learning show an expansion of structure that's both surprisingly extensive — there's a dramatic increase in the size and complexity of the affected neurons — and yet highly restricted to a small subset of cells.