Sentences with phrase «to infect human cells»

Greber and his team infected human cells in culture with the chemically labeled viruses, and observed the behavior of the viral DNA during entry into cells.

To do this, a team led by Matthew Weitzman of the University of Pennsylvania crosslinked the host factors of infected human cells with the DNA of adenovirus, herpes simplex virus and vaccinia virus.

To confirm these findings, the team infected human cells in dish with two forms of CMV — one of which could generate the IE2 accelerator circuit and one that could not.

Their assay was designed to identify compounds that blocked the ability of the Ebola virus to enter and infect human cells by at least 50 percent.

Then, by placing surface proteins of each HCV virus onto these pseudoviruses, the researchers were able to efficiently infect human cells with the HCV strains in tissue culture.

Knowledge of this structure, called the cytoplasmic tail of gp41 protein, will help researchers further understand how the virus infects human cells and how progeny viruses are assembled and released from infected cells.

The research showed the beta - lactamase genes in Klebsiella pneumoniae were on all the time, whether or not the bacteria were infecting human cell cultures.

First, we would expect variants that succeed in a plague epidemic to be better at infecting human cells and spreading more efficiently among humans than strains circulating in rats or other hosts.

MiRNA - seq, in conjunction with mRNA - seq is a key part of this project as understanding miRNAs produced by T. gondii - infected human cells relevant to human diseases will be valuable for those working in the field.

The protein, they found, preferentially binds to human endothelial cells, allowing the retrovirus, which would not normally infect human cells, to enter them.

«This new retrovirus may be able, through infecting human cells, [to] induce a transcription of an endogenous virus,» says Huber, who has been studying the presence of an ancient retrovirus (HERV - K18) dormant in most people but active in patients with CFS and multiple sclerosis.

Following a single treatment with CRISPR / Cas9, viral fragments were successfully excised from latently infected human cells embedded in mouse tissues and organs.

Last year, a team led by Gavin Screaton of Imperial College London found that Zika virus is far more likely to infect human cells if researchers first spike them with dengue antibodies.

But even if XMRV is not a threat to human health, the fact that a retrovirus that can readily infect human cells was apparently generated by chance in the lab raises some interesting and potentially troubling issues.

For instance, the way Zika infects human cells and hijacks their machinery to copy itself many times has proved elusive.

Now, researchers say, they have found that bats in China are carrying a closely related virus — one that can directly infect human cells and could potentially cause the next global pandemic.

MiRNA - seq and mRNA - seq will be carried out from the same RNA sample thereby integrating the mRNA and miRNA «sequenomes» of infected human cells most relevant to human toxoplasmosis.

Temporal Dynamics of Cytomegalovirus Chromatin Assembly in Productively Infected Human Cells.

Newburg and his collaborators are also studying a human - milk fat that seems to inhibit HIB from infecting human cells, and yet another milk component that prevents hiv from disabling the host's immune cells.

Both kill upwards of a third of people infected and, like many viruses, emerged from animals — bats and camels in the case of MERS — after mutating into a form capable of infecting human cells.

Viruses have their own genetic material and can infect human cells in a very specific manner.

Thirty years ago he engineered a bacterial strain to produce an HIV enzyme so he could study how it enables HIV to infect human cells.

An Australian research team, however, recently reached a milestone when it became the first to screen and catalogue all of the genes activated by a BSL4 pathogen when it infects human cells.

«We had assumed that pig tissues were more safe than baboon tissues, but now we see they can infect human cells,» Allen says.

For the first time, scientists have discovered a pig retrovirus that infects human cells.

High used AAV to deliver the gene because the virus is considered benign; although it infects human cells, it is not known to cause any symptomatic infection.

In laboratory studies reported in the Proceedings of the National Academy of Sciences (PNAS), the researchers found that these «neutralizing» antibodies prevented a key part of the virus, known as MERS CoV, from attaching to protein receptors that allow the virus to infect human cells.

Chinese horseshoe bats like this one carry a SARS - like virus that can infect human cells.

MxA is thought to target influenza A by binding to the nucleoprotein that encapsulates the virus» genome, and mutations in this nucleoprotein have been linked to the virus» ability to infect human cells.

Prior research has shown that the dengue virus (DENV) protein NS1, which is secreted by infected human cells, is a likely culprit behind such leaks.

Rational engineering of enzymes with improved anti-HIV properties: We collaborate with experimental groups (Prof. Buchholz, TUD) in the generation of new DNA recombinases with improved properties to excise HIV from infected human cells.

Now, a novel computational method shows that a viral protein found in EBV - infected human cells may activate genes associated with increased risk for autoimmunity.

If AAV is exclusively used to infect human cells, it stably i

When other researchers studied the virus in patients with PML, they found a mutation in its protein shell, the part that allows it to bind to and infect human cells.

«Once it infects a human cell, the virus could interact with human enzymes to produce these small RNAs, which could in turn alter brain development and lead to microcephaly.»