Sentences with phrase «to target molecules»

Traditionally, scientists have tried to approach the problem of cancer migration by targeting molecules inside cancer cells, but finding an appropriate target has proved challenging.

They enable oxidation by keeping target molecules in place and bringing them into contact with oxygen.

Most famous is an antibody that targets a molecule on immune cells called PD - 1.

Researchers have identified several target molecules which are suitable for the development of new allergy drugs.

The protein is found throughout the body, making it difficult to target the molecule specifically in the brain.

Potential therapeutic target molecules in these pathways will be highlighted in the conference.

Once the sensors have traveled into a tumor's leaky blood vessels, they use special targeting molecules to bind to receptors on the surface of blood vessel cells.

To better comprehend the role of each enzyme, researchers need to develop targeted molecules that can selectively shut off their function.

These treatments work by targeting molecules that serve as checks and balances in the regulation of immune responses.

Our laboratory investigates the role epigenetic regulatory proteins play in the progression of colon cancer and other gastrointestinal malignancies, with the goal of targeting these molecules as a potential treatment for these diseases.

A chemical interaction with target molecules subtly alters the magnetic signal from the xenon; by detecting this change researchers can identify the molecules in a complex mixture.

«Our study shows, for the first time, that BPA affects dental cells, and subsequently enamel synthesis, using similar target molecules as those present in other organs,» Babajko said.

The pair focused on the monoclonal antibody canakinumab, already approved for juvenile arthritis, because it selectively targets a molecule called IL - 1β, which is part of the pathway driving atherosclerosis.

We are interested in the mechanistic function and structure of antimicrobial / antifungal proteins and peptides and the identification of target molecules for the development of new antimicrobial / antifungal therapies.

High quality coating of magnetic silica beads with Steptavidin, Protein A, Protein G or other ligand specific molecules allows isolation of specific target molecules or cells out of large volumes or complex mixtures.

The Mast Cells and Basophiles: Targets for Innovative Therapies project, funded by COST funding BM1007 of the EU, brings together European experts focusing on the identification of new target molecules for drug development, including allergy drugs.

The reagent selectively targets molecules that contain carbonyl groups.

Performed pro-bono work investigating small cap pharmaceutical companies, ensuring scientific and clinical relevance for target drugs, revenue forecasting, market research for drugs with similar target molecule

A JCAP study shows that nearly 90 - percent of the electrons generated by a semiconductor / cobaloxime hybrid catalyst designed to store solar energy in hydrogen are being stored in their intended target molecules.

Lanza also designed the nanoparticles to carry targeting molecules that home in on and bind to cancer cells that carry the complementary receptor, like a lock and key.

Nowadays, catalysts come in a wide range of shapes and sizes — often rivalling the complexity of the actual target molecule.

Recent examples include: Targeted Molecules Raises $ 4,000,000 in Financing [San Diego, CA].

Draths and Frost targeted this molecule as the key to making adipic acid.

Even so, the identification of an LF target molecule represents the first step toward identifying compounds that can counteract the toxin — which could be a boon if the anthrax bacillus were to be used in a terrorist attack.

Given the potential for living systems to produce highly complex chemical compounds, researchers working with Michelle C.Y. Chang at the University of California, Berkeley (USA), aimed to manipulate the biosynthetic machinery in cells to use simple fluorinated building blocks to make new organofluorine target molecules.

«Using artificial intelligence is going to really accelerate the way we produce much better targeted molecules.

Moreover, small amounts of singlet oxygen produced during metabolic reactions can act as a local signaling factor that oxidizes and modifies target molecules, but the underlying mechanisms are poorly understood.

The techniques are so sensitive that they can detect even a few target molecules in a few micrograms of material, says physical chemist Pascale Richardin, a co-author of the study.

This makes the process very fast, but results in a lot of palladium either being wasted (because it gets thrown out after target molecules are harvested) or being recovered at high cost (because the recovery process is expensive).

And XNAs can evolve: When the researchers subjected billions of unique XNA strands to selective pressure in a test tube — in this case binding to a provided target molecule — out came XNA sequences folded up into 3 - D structures that could bind.

Scientists are designing new, more targeted molecules that might kill pain as well as today's opioids do — with fewer side effects.

But the full potential of CARs for treating solid tumors has not been reached because they have targeted molecules found on the surface of both normal cells and cancer cells, resulting in serious side effects.

«Our hyperpolarization technique based on optically polarized NV centers is far more robust and efficient and should be applicable to arbitrary target molecules, including biological systems that must be maintained at near ambient conditions.»

When enough RAP molecules adhere to enough target molecules, staph bacteria switch on their cell - to - cell communication and stress - response systems and begin producing the toxin that makes them so lethal.

When the aptamer and target molecule connect, the DNA strand unzips and the clam opens up, releasing its payload.

An approach to treating HD that uses targeted molecules to tell cells not to produce the harmful huntingtin protein

Olaparib targets a molecule called PARP, and exploits weaknesses in cancer cells» ability to repair damage to their DNA.

Sensing materials are aimed at sequestrating target molecules of interest in extremely low concentrations (down to the femto molar range).

The long - range trapping possible in our technique can be used to design fast and efficient sensors that capture target molecules and particles within a trapping zone that extends far above the surface.»

Current industrial processes to make alcohols and aldehydes require starting with a complex, petrochemical - based target molecule, an olefin, which is then converted to liquid chemicals in a complicated series of several steps.

Furthermore, we develop and functionally characterize novel additional targeting molecules that will be included into the system.

Monoclonal antibodies (mAbs) are special «magic bullets» that can be manufactured to recognize target molecules on the surface of cancer cells.

«Gene therapy, or any treatment that relies on tight regulation of gene expression, could be improved by precisely targeting molecules to the right place in the nucleus,» says Karpen.

«Ovarian cancer target molecule may be key to blocking its spread.»

Keith Pardee, a colleague of Collins, improved the test by inserting tailor - made gene switches that prevent any colour change happening unless a very specific target molecule is present.

As a thiol - containing metabolite, cysteamine is suspected to engage disulfide bridges with target molecules.

The researchers modified a type of human immune cell — called T lymphocytes, or T cells — to target a molecule called CS1, which is found on more than 95 percent of myeloma cells, and to kill the cells.

«Thus, FKBP10 represents a potential new target molecule for the individualized therapy of IPF,» said Claudia Staab - Weijnitz.

Several target molecules have also been identified in intracellular signalling pathways and in cell survival proteins.