Sentences with phrase «to trigger cell death»

The sensor did not trigger cell death in response to other similar viruses or to bacteria.

If the tail is bound and made inaccessible using a further antibody, activation of the switch can likewise no longer trigger cell death.

Once the scientists identified that pathway, they began to search for the protein molecule that actually recognizes the virus and triggers the cell death machinery.

But the Israeli researchers have shown that the receptors can trigger cell death simply by binding to one another.

The discovery, which is described online in the journal Cell, may lead to new ways to trigger cell death in some types of cancer cells.

In a study published in 2006, he and other Johns Hopkins researchers tested two compounds similar to CGP3466B to see if they would block GAPDH from triggering cell death under the types of highly stressful conditions that would normally cause apoptosis.

It turned out that one compound, called CP - 31398, was indeed triggering cell death — but not by restoring p53.

Other plasma - activated solutions have previously been shown to induce reactive oxygen species within cells, but these were not detected in plasma - activated Lactec (PAL)- treated cells, suggesting an alternative mechanism triggered cell death.

These damaged molecules trigger cell death that produces some human diseases, according to the researchers.

«Nutrient deprivation kills kidney cancer cells: Cutting off amino acid triggers cell death in cancers.»

PSD - 95 inhibitors interfere with the process that triggers cell death when the brain is deprived of oxygen.

The team identified a critical pathway of molecular signals which throw a lifeline to cancer cells, enabling them to survive even though they contain vast DNA errors which would usually trigger cell death.

«Dying C. elegans also undergo what we term a «belly punch» phenomenon where death contraction in the head drives the pharynx backwards into the intestine, and the impact triggers cell death,» added Professor Gems.

Once a woman sails past her mid-thirties, her eggs increasingly succumb to apoptosis, or internally triggered cell death.

But it's much harder to develop therapies that restore malfunctioning genes that should be triggering cell death in abnormal cells, known as tumor - suppressor genes.

Abnormal chromosome ends can stimulate DNA repair mechanisms and trigger cell death, while one of the roles telomeres play is to ensure a normal cell cycle.

When Snyder saw the paper, he connected it to his team's findings, inferring that CGP3466B might work by preventing GAPDH from entering the nucleus to trigger cell death.

This leads to telomere shortening over time, which has been thought of as a time - delay «fuse» that can trigger cell death or genomic instability.

There, he guided the animal studies for Fasaret, a cancer therapeutic that triggers cell death, launching the product into phase I clinical trials.

But if the stress isn't relieved in a timely fashion, it triggers cell death.

Copper kills by undergoing a chemical reaction with oxygen that destroys the cell walls of most bacteria, triggering cell death.

«As normal cells far outnumber the cancer cells in patients, we sought to empower the normal cells to trigger cell death in p53 - deficient cancer cells,» said Rangnekar, associate director of transdisciplinary collaborations for the UK Markey Cancer Center.

In the study, published in Cell Reports, the University of Kentucky's Vivek Rangnekar and his colleagues activated wild type p53 in normal cells to trigger cell death in the p53 - deficient cancer cells.

In the new study, Lipton and his colleagues used human stem cell and mouse models to show exactly how SNO can trigger cell death in Parkinson's disease.

These genes are more active in the young cave fish than in their sighted counterparts — an elevated level of activity that triggers cell death in the eye's lens.

We're using it to try to reveal a new pathway to trigger cell death in these cancer cells that have traditionally been considered very resistant to cell death,» said Ishmael.

Drugs can not reach the tissue at lethal doses because its blood supply is so poor, while radiation treatments depend on oxygen to trigger cell death.

The active ingredient in aspirin blocks an enzyme that triggers cell death in Alzheimer's, Parkinson's and Huntington's diseases, offering hope for novel treatments.

NK cells kill infected cells by releasing small cytoplasmic granules that trigger cell death (apoptosis).

By mimicking a molecular switch that triggers cell death, researchers have killed cells grown in the laboratory from one of the most resilient and aggressive cancers - a virulent brain cancer known...

This occurs because the Epstein - Barr virus can both switch on genes in the B cells that drive growth and turn off other genes that trigger cell death.