Sentences with phrase «transgenic mouse lines»

To this end, another PhD student in the lab, Ji - Feng Fei, generated a novel transgenic mouse line.

AβPP transgenic mouse lines differ in the types and amounts of Aβ that they generate and in their spatiotemporal patterns of expression of Aβ assemblies, providing a toolkit to study Aβ amyloidosis and the influence of Aβ aggregation on brain function.

For her dissertation, Prerana developed several bacTRAP transgenic mouse lines to characterize molecularly distinct cortical pyramidal cell types, and focused on layer 2/3 pyramidal cell population in the prefrontal cortex that moderate stress induced depression related behavior.

The mice were crossed with Slc6a14 − / − mice to generate these two transgenic mouse lines on Slc6a14 + / + and Slc6a14 − / − backgrounds.

One of the most popular models is the immunodeficient nonobese diabetic severe combined immunodeficiency (NOD scid) gamma (NSG) transgenic mouse line, which can be endowed with a humanized immune system using CD34 + hematopoietic stem cells.

From pronuclear injections of this construct, a total of four transgenic mouse lines (Z111A, Z111B, Z116A, and Z116B) were obtained containing independently segregating insertion sites.

The transgenic mouse line APPswe / PS1ΔE9 85 was a generous gift of Dr. J.L. Jankowsky.