Sentences with phrase «tumour formation»

Finally, this study was performed nearly identically to the first on UVB rays and it again observed a decrease in tumour formation when olive oil was applied after UVB ray exposure.

According to Eckmann, «The special thing about these processes is that they involve known molecules with very long evolutionary histories, previously receiving attention as suppressors of tumour formation within the context of normal cell division.

The immune response triggered by eczema could help prevent tumour formation by shedding potentially cancerous cells from the skin.

Researchers theorize that this further helps protect the naked mole - rat by reducing the chance for tumour formation.

Olive oil significantly reduced the rate of UVB - induced tumour formation when applied after exposure, and when applied before exposure, the formation of new tumours slowed down.

The findings suggest that defects in the epidermal barrier protected the genetically engineered mice against benign tumour formation.

The researchers studied ferric citrate and ferric EDTA, which have both previously been shown to worsen tumour formation in mice with colon cancer.

What remains unclear is whether cancer stem cells are the direct progeny of mutated stem cells or more mature cells that reacquire stem cell properties during tumour formation.

Possible prevention of cancer due to increasing the activity of a protein called P53, which suppresses tumour formation.

Both inhibited tumour formation and skin elasticity decreases from sunlight, in an oral test.

So reducing the risk of tumour formation or discovering a way to produce mature sperm in a test tube will have to be developed before we can even consider this in humans.»

This suggests that molecular mechanisms that have evolved to promote tissue repair are closely related to those involved in tumour formation, which could help us understand cancers.»

«However, our study has identified a number of other HAS2 gene mutations that are predicted to have a significant effect on hyaluronan production, opening up exciting new avenues of research into the pathways whereby HMM - HA prevents tumour formation.»

Using a bioinformatics approach, we have identified the relevant signalling pathways that make dense breast tissue more favourable for tumour formation.

The JNK1 network is known to instruct cells to release chemicals that create an inflammatory environment and inflammation is known to be a driver of tumour formation.

This could potentially be used to turn off the expression of certain genes that are involved in tumour formations.

Dr Mike Turner, Head of Infection and Immunobiology at the Wellcome Trust, said: «Skin cancer is on the rise in many countries and any insight into the body's ability to prevent tumour formation is valuable in the fight against this form of cancer.

Genes identified by the research team — led by the Universities of Edinburgh, Cambridge and University College London — were also found to be similar to those seen in tumour formation, which could shed light on cell growth in cancers.

These findings provide the largest analysis of viruses in tumours and preclude a broad spectrum role of viruses in tumour formation.

The work, published this week in Nature Communications, provides a comprehensive dataset for understanding the role of viruses in tumour formation.

NF 1 and 2 are complex multi-system diseases that have a major impact on the nervous system and pre-dispose to tumour formation.

MYC's role in tumour formation has stretched to include hiding cancers from the immune system.

The commentary highlights the possible fundamentally different and even opposing functions of intestinal fibroblast subpopulations in regulating inflammation and tumour formation and underscores the need to further characterize these cells to reveal new mechanisms underlying pathogenesis of chronic inflammation and cancer.

Chimeric mice made with the «3 - factor» mouse iPS cells did not develop obvious tumours, while those made also using cMyc did, which suggests that tumour formation was indeed due to abnormal cMyc expression rather than some general problem of the reprogramming method.

Upon orthotopic transplantation into immunodeficient mice, these organoids form normal pancreatic ducts and acinar tissue resembling fetal human pancreas without evidence of tumour formation or transformation.

In the mouse experiments no tumour formation was found (within 100 days).

Therefore, in some cases the process of inserting the healthy gene can increase the activity of cancer - linked genes, leading to tumour formation.

Use of gene therapy in conjunction with a new genome - editing technology, CRISPR / Cas9, would allow the specific insertion of the healthy gene into sites in the genome that are known to be located far away from cancer - linked genes, reducing the risk of tumour formation.