Sentences with phrase «variety of cells»

«We've shown that SIF - seq can be used to identify enhancers active in cardiomyocytes, neural progenitor cells, and embryonic stem cells, and we think that it has the potential to be expanded for use in a much wider variety of cell types,» Dickel says.

Visel, Pennacchio, Dickel and their colleagues developed SIF - seq in response to the need for a higher - throughput functional enhancer assay that can be used in a wide variety of cell types and developmental contexts.

Under physiological conditions, ROS are important mediators of a wide variety of cell functions through their actions on redox - sensitive transcription factors.

«Further research are required on a greater variety of cell types and their intracellular differences to achieve more in - depth information on the physicochemical and mechanical differences between male versus female cells.

The IFNGR receptor is one of these membrane proteins and undertakes to activate genes involved in a huge variety of cell processes, including defence against pathogens and cancer.

Mice have way fewer brain cells than humans, and way fewer varieties of these cells.

«If you are an experimental biologist, in your experiments you see an amazing variety of cell types.

The team demonstrated that cell sex considerably influenced cellular uptake of nanoparticles and found that cells from men and women responded differently to reprogramming techniques used to enhance the ability of the cells to differentiate into a greater variety of cell types.

The cortex is the thin layer of cells on the surface of the brain that governs many functions, and in elephants it contains a greater variety of cell types (such as the extensively branched neuron pictured above) than is found in more frequently studied animals such as rodents and primates.

There are four histamine receptors found on a wide variety of cells in the body.

«However, because SIF - seq only requires DNA sequence from a mammal and can be used in a variety of cell types, it should be possible to compare the neuronal enhancers present in a large genomic region from human to the neuronal enhancers present in the orthologous chimpanzee region.

Previous research shows human induced pluripotent stem cells (hiPSCs)-- generated directly from adult cells — can express markers for a wide variety of cells, including those that secrete NP.

BK channels are potassium ion channels found on the surface of a variety of cell types that are essential for the regulation of several key physiological processes, including smooth muscle tone and neuronal excitability.

Someday, researchers could «plug and play» programmed DNA into a variety of cells to address a variety of diseases, said study author Wilfred Chen, Gore Professor of Chemical Engineering.

This is particularly important as it indicates the method can be used in a variety of cell types to create disease models and contribute to the discovery of new disease - specific therapeutics.

Chemokines are produced by a variety of cell types, including connective tissue cells called fibroblasts.

It could be that the Epstein - Barr virus primarily infects B cells whereas cytomegalovirus can hide in a variety of cell types.

Within our fat lives a variety of cells with the potential to become bone, cartilage, or more fat if properly prompted.

He learned that a variation in the DNA of the cells that make antibodies results in a variety of cell types, each with a unique antibody molecule on its surface.

«As progenitor cells, they have the capacity to differentiate into a variety of cells, including neurons.

The eye is composed of highly specialized tissues that are derived from a variety of cell lineages during development.

The EMT is a biological process wherein epithelial cells (cells that line the cavities and surfaces of blood vessels and organs) become mesenchymal (skeletal) stem cells that can move throughout the body and differentiate into a variety of cell types.

In the broadest sense, this variation in shapes is known as cell polarity, and it is an essential property for a variety of cell functions.

They then turn into a variety of cells to repair the retina.

Intracellular reduction - oxidation reactions underlie a variety of cell functions including energy metabolism, signaling, and transcriptional processes.

Researchers from the University of Cambridge studied a variety of cell lines, including human neural stem cells, to investigate how Zika virus infection can lead to microcephaly.

Stem cells are unique in that they can adopt the shape and function of a variety of cell types.

One reason might be because of the characteristics of gingival mesenchymal stem cells, or GMSCs, which can give rise to a variety of cell types.

In addition to being the vector of choice for gene delivery to a variety of cell types, now you know that AAVs can provide a powerful boost to genome editing experiments.

Work led by Dr. Blackwell is studying mechanisms that allow cells to maintain a «pluripotent» state that enables them to become a variety of cell types, including beta cells.

More recently, we have adopted the rapidly developing CRISPR - cas9 system to generate protein - null genetic mutants in a variety of cell types.

The variety of cell types present in BALF may reflect the degree of inflammation in the peripheral airways, which is also the main factor causing bronchial hyperresponsiveness in asthma (25).

I use a variety of cell and animal models including goats, and mice.

The tumors arising in p21 - null mice derive from a variety of cell types and include hematopoietic (∼ 65 % of the tumors), endothelial (∼ 20 %), and epithelial (∼ 10 %) tumors.

Embryonic and fetal stem cells have the potential to morph into a greater variety of cells than adult stem cells do.

Though scientists understand the primary jobs of blood's contents, they're learning that a variety of cells work together in complicated ways, says Donna DiMichele, deputy director of the Division of Blood Diseases and Resources at the National Heart, Lung, and Blood Institute, part of the National Institutes of Health located outside Washington, D.C. Blood cells and even blood vessels respond to situations within the body by releasing a range of chemicals.

An expansive portfolio of chemically defined and xeno - free laminin proteins for a variety of cell culture applications

We have gone on to show that the sensitivity of the germ line genome instability differs across inbred strains of mice, offering a unique opportunity to use systems genetics approaches to discover the underlying pathways governing cell division and survival across a variety of cell types.

No matter how pure, in any unprocessed biological sample there are a variety of cells representing various tissue types.

It was found that a variety of cells could have their «established» identities altered, with a group in 2008 reporting that some pancreas cells (exocrine cells) could be turned into other, insulin - producing pancreas cells (beta - cells), which may hold promise for treating diabetes.

In addition to iPS cells derived from progeria - patients, the researchers successfully applied their method to adult mesenchymal stem cells, which can differentiate into a variety of cell types, including adipocytes, osteoblasts, chondrocytes, cardiomyocytes, and, as described lately, beta - pancreatic islets cells.

These cells, found in human embryos or fetal tissue, have the unique ability to change into a variety of cell types — blood, heart, nerve, muscle, etc. — that form most of the body's tissues and organs.

They are pluripotent, differentiating into a variety of cell types that include cells of the peripheral nervous system, cartilage, bone, and melanocytes.

To date, scaling up human tissues built of a variety of cell types has been limited by a lack of robust methods for embedding life - sustaining vascular networks.

These «repair cells» can differentiate into a variety of cell types including heart muscle and blood vessels.

The immune system consists of a wide variety of cell types that function in unison to combat disease.

To achieve a variety of tissue shapes, thicknesses, and composition, the shape of the printed silicone chip can be customized and the cell inks can be tuned to include a wide variety of cell types.