«We've shown that SIF - seq can be used to identify enhancers active in cardiomyocytes, neural progenitor cells, and embryonic stem cells, and we think that it has the potential to be expanded for use in a much wider variety of cell types,» Dickel says. (sciencedaily.com)
Visel, Pennacchio, Dickel and their colleagues developed SIF - seq in response to the need for a higher - throughput functional enhancer assay that can be used in a wide variety of cell types and developmental contexts. (sciencedaily.com)
Under physiological conditions, ROS are important mediators of a wide variety of cell functions through their actions on redox - sensitive transcription factors. (journals.plos.org)