Synthetic lethality refers to a concept where two genetic changes or mutations, which individually do not cause harm, become deadly when combined. It means that when two specific alterations occur together, they generate a lethal or harmful effect. This concept is often used in cancer research to discover new ways to target and treat tumors.
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Synonyms for individual words can be found below.
«synthetic»
«lethality»
Sentences with «synthetic lethality»
- Series A investors include 5AM Ventures, Canaan Partners, Celgene, WuXi Healthcare Ventures, Novartis Institute of Biomedical Research, and Alexandria Real Estate Small molecule programs with focus on synthetic lethality and... (ideayabio.com)
- IDEAYA is pioneering the next generation of biomarker - enabled synthetic lethality therapies for genetically defined patient populations and advancing an immuno - oncology pipeline targeting immuno - metabolism and innate immunity. (ideayabio.com)
- 3) Unni A *, †, Lockwood WW *, †, Zejnullahu K, Lee - Lin S, Varmus H (2015) Evidence that synthetic lethality underlies the mutual exclusivity of oncogenic KRAS and EGFR mutations in lung adenocarcinoma. (bccrc.ca)
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