They found that seasonal flu escapes immunity and develops into new strains typically by just a single amino acid substitution. (sciencedaily.com)
In nature, advantageous amino acid substitutions may be promoted by positive selection, but the general structural distributions of positively selected mutations and their effects on protein function remain poorly examined. (sciencedaily.com)
Scientists have identified a potential way to improve future flu vaccines after discovering that seasonal flu typically escapes immunity from vaccines with as little as a single amino acid substitution. (sciencedaily.com)