However, telomerase, the enzyme, which can synthesize telomeres, may also support the survival of aneuploid cells by alleviating telomere induced stress signals in response to aneuploidy. (sciencedaily.com)
Pre-malignant aneuploid cells grew more slowly and formed smaller tumors than comparable cells with normal chromosome number.» (sciencedaily.com)
Having an irregular number of chromosomes, almost by definition, leads to imbalances in the numbers of proteins expressed in aneuploid cells. (sciencedaily.com)