Primary congenital aphakia is a rare development disorder, characterized by the absence of lens developed between the 4th and the 5th week of embryogenesis. (doctor-info.website)
A study of Valleix et al. (2006) identified homozygous mutation of FOXE3 gene on 1p33 chromosome in three brothers with aphakia born by consanguineous parents. (doctor-info.website)
Secondary aphakia concerning in partial development of the lens due to late reabsorption or eventually due to expulsion through a corneal perforation (1). (doctor-info.website)