The Nefedova laboratory focuses on understanding the role of bone marrow microenvironment in regulation of tumor progression and therapy resistance. (wistar.org)
Nefedova studies molecular mechanisms by which bone marrow microenvironment promotes tumor survival and progression. (wistar.org)
Basic research has centered on identifying and characterizing hematopoietic stem cells, however, it is still not clear how hematopoietic stem cells actually work, and how they are regulated because of the complexity of the bone marrow microenvironment. (sciencedaily.com)