The word "breakthrough" means a major accomplishment or discovery that marks a significant progress or advancement in a particular field or situation. Full definition
The rapid technology development is expected to lead to more exciting discoveries of the ocean and its physics, chemistry, and biology, which may result in breakthrough in earth system science. (oceanobs19.net)
Legal technology has reached a lot of breakthroughs for solo practitioners. (deallawblog.com)
It is the latest in a series of breakthroughs in ancient DNA, coming just months after the sequencing of the oldest - ever genome, from a 700,000 - year - old horse. (newscientist.com)