Here we show that an abundant stromal cell population, cancer - associated fibroblasts (CAFs), promote cancer cell invasion through the BM. (science.institut-curie.org)
By screening already approved drugs, the team led by Postdoctoral Researcher Guillaume Jacquemet and Academy Professor Johanna Ivaska has discovered that calcium channel blockers can efficiently stop cancer cell invasion in vitro. (sciencedaily.com)
Thus, in a panel of breast cancer samples, we identified tumor cells that did not form part of the bulk tumor mass, but instead were interspersed within the adjacent stroma — as if forming the forefront of cancer cell invasion. (impactjournals.com)