They will test the best candidate molecules in mice to see if they can replicate their study findings, before moving on to human clinical trials. (sciencedaily.com)
Over the past couple of decades, the screening of molecules for their active principle has relied greatly on the ability to model candidate molecules before experimental consideration. (qmcpack.org)
This system, along with computer modeling and further tests performed both in and outside of cells, whittled the thousands of candidate molecules down to eight that could bind to SENP2 in cells and were non-toxic. (sciencedaily.com)