Phrases with «checkpoint molecules»

"Checkpoint molecules" refer to certain proteins found on immune cells that act as signals to either activate or inhibit the immune response in the body. They help the immune system maintain a balance in regulating the immune response to prevent it from becoming too weak or overly active. Full definition

checkpoint molecules

Sentences with «checkpoint molecules»

«Although we found that chemotherapy activated the T cells, the levels of the protein PD - L1 [to which the immune checkpoint molecule PD - 1 binds to disable T cells and prevent them from recognizing and destroying the cancer cells] remained the same or increased. (sciencedaily.com)
AMD3100, alone or in combination with VIC - 008, decreases expression of the immune checkpoint molecule PD - 1 on CD8 T cells, implying that the CXCR4 / CXCR12 pathway modulates PD - 1 expression. (sciencedaily.com)
Monitor the expression of B7 - H1 / PD - L1 and other checkpoint molecules with antibodies suitable for IHC, flow cytometry, and Western blot. (rndsystems.com)
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Phrases with «checkpoint molecules»

Sentences with «checkpoint molecules»

See also