Surprisingly, the researchers found a similar bimodal 3 - dimensional chromatin architecture in the Hoxd gene region in zebrafish embryos. (sciencedaily.com)
The lab investigates consequences of epigenetic alterations in neuronal cancers and neurodegenerative diseases using a combination of biochemistry, cell and molecular biology with genome wide approaches to gain mechanistic insight into how chromatin architecture is modified in disease. (wistar.org)
We have demonstrated that the regulatory regions of housekeeping and tissue specific genes have differential chromatin architecture with respect to S / MAR binding, nucleosome positioning potential and repetitive sequences. (bmcbioinformatics.biomedcentral.com)