The Noma laboratory has studied 3D chromosome organizations in the fission yeast model organism and the more complex human system. (wistar.org)
Next, Dekker and the team, led by Leonid Mirny, PhD, associate professor at the Massachusetts Institute of Technology, developed sophisticated computer simulations using polymer models of the DNA molecule for the two competing theories for mitotic chromosome organization. (sciencedaily.com)
Recent studies have started to map the gene - wide chromatin interactions in the interphase nucleus, revealing some principles of chromosome organization into territories, and dramatic changes of chromatin organization and interactions during differentiation and lineage specification. (dresden-ipp.de)