Phrases with «conditional knockout»

The phrase "conditional knockout" refers to a scientific technique used in genetics research. It involves turning off or "knocking out" a specific gene in an organism under certain conditions, like at a specific stage of development or in a particular body tissue. This approach helps scientists study the function of that gene and understand its effects on the organism. Full definition

Sentences with «conditional knockout»

  • We use what are called conditional knockout mice, in which a gene is deleted only in a specific organ or group of cells. (kavlifoundation.org)
  • Conditional knockout of Uhrf1, in a region of the forebrain, led to the activation of endogenous retroviral elements (ERV) in the genome, which are otherwise silenced by methylation. (sciencedaily.com)
  • «Eliminating endothelial CD146 by conditional knockout in two different mouse models of colitis significantly reduced the severity of inflammation and decreased tumor incidence and tumor progression in a mouse model of CAC,» reports lead investigator Xiyun Yan, PhD, from the Key Laboratory of Protein and Peptide Pharmaceuticals, Institute of Biophysics, Chinese Academy of Sciences, Beijing. (sciencedaily.com)
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